Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 19/20 | 0.67 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30877515 | 1.00 | NAMPT (0.67) | NAMPTNPC1RAB9A | |
| SCHEMBL3702359 | 0.84 | NAMPT (0.68) | NAMPT | |
| SCHEMBL3703713 | 0.83 | NAMPT (0.77) | NAMPTNPC1RAB9A | |
| SCHEMBL24947597 | 0.82 | NAMPT (0.68) | NAMPTNPC1RAB9A | |
| SCHEMBL3697374 | 0.81 | NAMPT (1.00) | NAMPT | |
| SCHEMBL3706031 | 0.78 | RAB9A (0.81) | NAMPTNPC1RAB9A | |
| SCHEMBL3705220 | 0.78 | NAMPT (1.00) | NAMPT | |
| SCHEMBL20611950 | 0.76 | NAMPT (0.55) | NAMPTNPC1RAB9A | |
| SCHEMBL3705990 | 0.76 | NAMPT (1.00) | NAMPT | |
| SCHEMBL3698598 | 0.76 | NAMPT (0.73) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023007147-A1 | 6-SUBSTITUTED NAPHTHALENE-1,3-DISULFONIC ACID DERIVATIVES AS MODULATORS OF THE EXTRACELLULAR NICOTINAMIDE PHOSPHORIBOSYL TRANSFERASE (ENAMPT) FOR THE TREATMENT OF E.G. DIABETES | THE UNIVERSITY OF MANCHESTER (GB) | 2023-02-02 | — | — | WO | disclosed |