SCHEMBL24948897

SCHEMBL24948897

Clc1ccc(-c2ccccc2-n2c3ccccc3c3ccc4ccccc4c32)c(-c2ccccc2)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APAF1 O14727 1/20 0.36
MAPK14 Q16539 1/20 0.36
IDO1 P14902 1/20 0.34
TDO2 P48775 1/20 0.34
IDO2 Q6ZQW0 1/20 0.34
MDM2 Q00987 1/20 0.33
S100A4 P26447 1/20 0.33
CYP1A2 P05177 4/20 0.33
CYP1B1 Q16678 4/20 0.33
BMX P51813 1/20 0.33
MCL1 Q07820 1/20 0.32
BAD Q92934 1/20 0.32
SERPINE1 P05121 1/20 0.32
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32
PTGDR2 Q9Y5Y4 1/20 0.32
DNMT1 P26358 1/20 0.32
EGFR P00533 1/20 0.32
CYP1A1 P04798 3/20 0.32
BRD4 O60885 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24948287 0.90 APAF1 (0.41) APAF1MAPK14IDO1TDO2IDO2
SCHEMBL24948304 0.87 S100A4 (0.40) APAF1MAPK14IDO1TDO2IDO2
SCHEMBL30724560 0.87 S100A4 (0.40) APAF1MAPK14IDO1TDO2IDO2
SCHEMBL25000011 0.85 S100A4 (0.38) APAF1MAPK14IDO1TDO2IDO2
SCHEMBL22783411 0.85 BMX (0.39) MAPK14CYP1A2CYP1B1BMXCYP1A1
SCHEMBL30724558 0.85 APAF1 (0.36) APAF1MAPK14IDO1TDO2IDO2
SCHEMBL24948965 0.85 APAF1 (0.36) APAF1MAPK14IDO1TDO2IDO2
SCHEMBL23205761 0.85 KDM4E (0.43) MAPK14IDO1TDO2IDO2CYP1A2
SCHEMBL24949675 0.84 APAF1 (0.37) APAF1MAPK14IDO1TDO2IDO2
SCHEMBL30724564 0.84 APAF1 (0.37) APAF1MAPK14IDO1TDO2IDO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023002447-A1 ORGANIC LIGHT-EMITTING DEVICE 주식회사 엘지화학 2023-01-26 WO disclosed
WO-2023003403-A1 ORGANIC LIGHT-EMITTING DEVICE 주식회사 엘지화학 2023-01-26 WO disclosed