SCHEMBL2494937

SCHEMBL2494937

COc1c(C)c(C)c(OC)c(OC)c1C

nearest known ligand 0.40

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.36
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPK1 P28482 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2952712 0.92 ACHE (0.40) ACHEKDM4EALDH1A1MAPK1SMN1; SMN2
SCHEMBL11308950 0.92 ACHE (0.40) ACHEKDM4EALDH1A1MAPK1SMN1; SMN2
SCHEMBL14217694 0.88 ACHE (0.38) ACHEKDM4EALDH1A1MAPK1SMN1; SMN2
SCHEMBL85826 0.88 ACHE (0.38) ACHEKDM4EALDH1A1MAPK1SMN1; SMN2
SCHEMBL16785663 0.88 ACHE (0.38) ACHEKDM4EALDH1A1MAPK1SMN1; SMN2
SCHEMBL2495732 0.85 ACHE (0.36) ACHEKDM4EALDH1A1MAPK1SMN1; SMN2
SCHEMBL8915846 0.81 ACHE (0.35) ACHEKDM4EALDH1A1MAPK1SMN1; SMN2
SCHEMBL14507695 0.81 ACHE (0.35) ACHEKDM4EALDH1A1MAPK1SMN1; SMN2
SCHEMBL12974023 0.79 ACHE (0.33) ACHEKDM4EALDH1A1MAPK1SMN1; SMN2
SCHEMBL6883720 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4011921-B1 RUBBER WITH BACKBONE AND END-GROUP FUNCTIONALIZATION AND ITS METHOD OF MANUFACTURING AND USE IN A TIRE G 3 CHICKADEE PURCHASER LLC 1485 E ARCHWOOD AVENUE (US) 2026-02-04 EP disclosed
CN-114621375-B Rubber with backbone and end-group functionalization 固特异轮胎和橡胶公司 2024-06-18 CN disclosed
US-11912798-B2 Rubber with backbone and end-group functionalization THE GOODYEAR TIRE & RUBBER COMPANY (US) 2024-02-27 US disclosed
US-20230312798-A1 FUNCTIONALIZED HYDROGENATED POLYMERS MIZUHO BANK, LTD., AS ADMINISTRATIVE AGENT 2023-10-05 US disclosed
EP-4011921-A1 RUBBER WITH BACKBONE AND END-GROUP FUNCTIONALIZATION AND ITS METHOD OF MANUFACTURING AND USE IN A TIRE The Goodyear Tire & Rubber Company (US) 2022-06-15 EP disclosed
CN-114621375-A Rubber with main chain and end group functionalization 固特异轮胎和橡胶公司 2022-06-14 CN disclosed
US-20220177610-A1 RUBBER WITH BACKBONE AND END-GROUP FUNCTIONALIZATION MIZUHO BANK, LTD., AS ADMINISTRATIVE AGENT 2022-06-09 US disclosed
EP-3313927-B1 DILITHIUM INITIATORS FINA TECHNOLOGY (US) 2021-12-15 EP disclosed
CN-107922678-B Dilithium initiators 飞纳技术有限公司 2020-04-07 CN disclosed
EP-3313927-A1 DILITHIUM INITIATORS Fina Technology, Inc. (US) 2018-05-02 EP disclosed
EP-0761703-A1 Isoprene-butadiene diblock rubber THE GOODYEAR TIRE & RUBBER COMPANY (US) 1997-03-12 EP disclosed
US-5534592-A POLYBUTADIENE RUBBER BLEND THE GOODYEAR TIRE & RUBBER COMPANY (US) 1996-07-09 US disclosed
EP-0438967-B1 Segmented elastomer GOODYEAR TIRE & RUBBER (US) 1996-05-01 EP disclosed
US-5239009-A Butadiene, isoprene, styrene random polymer, wear resistance, good traction tire treads THE GOODYEAR TIRE & RUBBER COMPANY (US) 1993-08-24 US disclosed
US-5202387-A Modified styrene-butadiene copolymer; catalytic polymerization using living-catalyst THE GOODYEAR TIRE & RUBBER COMPANY (US) 1993-04-13 US disclosed
US-5100965-A Process for synthesizing high trans polymers THE GOODYEAR TIRE & RUBBER COMPANY (US) 1992-03-31 US disclosed
US-5070148-A SEGMENTED ELASTOMER THE GOODYEAR TIRE & RUBBER COMPANY (US) 1991-12-03 US disclosed
EP-0438967-A1 Segmented elastomer THE GOODYEAR TIRE & RUBBER COMPANY (US) 1991-07-31 EP disclosed
EP-0258167-A2 Modifier for lithium catalysts THE GOODYEAR TIRE & RUBBER COMPANY (US) 1988-03-02 EP disclosed
US-4696986-A 1,2,3- OR 1,2,4-TRIALKOXYBENZENE MODIFIERS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1987-09-29 US disclosed