Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.33 |
| ▸ | GABRE | P78334 | 1/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30206576 | 1.00 | KDM4E (0.38) | KDM4EKMT2AALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL30206579 | 1.00 | KDM4E (0.38) | KDM4EKMT2AALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL13907994 | 0.73 | TPMT (0.41) | KDM4EALDH1A1SMN1; SMN2HSD17B10NOTUM | |
| SCHEMBL2582880 | 0.72 | MAPT (0.46) | KDM4EKMT2AALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL30206423 | 0.72 | MAPT (0.46) | KDM4EKMT2AALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL14086770 | 0.70 | TSHR (0.35) | KDM4EKMT2AALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL3525912 | 0.69 | HAO1 (0.33) | ALDH1A1HCAR2ALPLDHODH | |
| SCHEMBL12180620 | 0.67 | FABP6 (0.33) | ALDH1A1FABP6 | |
| SCHEMBL8309614 | 0.66 | KDM4E (0.48) | KDM4EKMT2AALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL10660689 | 0.66 | KDM4E (0.48) | KDM4EKMT2AALDH1A1MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006634-A1 | METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR | SYNGENTA CROP PROTECTION AG (CH) | 2023-02-02 | — | — | WO | disclosed |