SCHEMBL2582880

SCHEMBL2582880

Cc1cc2cn[nH]c2c(C(=O)O)c1N

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 1/20 0.46
▸ KDM4E B2RXH2 2/20 0.38
▸ KMT2A Q03164 1/20 0.38
▸ ALDH1A1 P00352 3/20 0.37
▸ MAPK1 P28482 1/20 0.37
▸ SMN1; SMN2 Q16637 1/20 0.37
▸ BTK Q06187 5/20 0.36
▸ TNK2 Q07912 2/20 0.36
▸ FGFR1 P11362 2/20 0.36
▸ LRRK2 Q5S007 2/20 0.36
▸ PLK4 O00444 1/20 0.36
▸ CHEK1 O14757 1/20 0.36
▸ AURKA O14965 1/20 0.36
▸ DAPK3 O43293 1/20 0.36
▸ MAP4K4 O95819 1/20 0.36
▸ CSF1R P07333 1/20 0.36
▸ RET P07949 1/20 0.36
▸ PDGFRA P16234 1/20 0.36
▸ LTK P29376 1/20 0.36
▸ KDR P35968 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30206423 1.00 MAPT (0.46) MAPTKDM4EKMT2AALDH1A1MAPK1
SCHEMBL4072321 0.84 TSHR (0.45) MAPTKDM4EKMT2AALDH1A1SMN1; SMN2
SCHEMBL4071766 0.81 CYP1A2 (0.39) MAPTKDM4EKMT2AALDH1A1MAPK1
SCHEMBL4083786 0.81 NOS1 (0.38) MAPTKDM4EKMT2AALDH1A1BTK
SCHEMBL4081049 0.81 CHEK1 (0.34) MAPTBTKTNK2FGFR1LRRK2
SCHEMBL4071770 0.78 LRRK2 (0.38) MAPTKDM4EBTKTNK2FGFR1
SCHEMBL551333 0.72 ACACB (0.48) ACACBACACA
SCHEMBL4083790 0.72 CHEK1 (0.46) MAPTKDM4EKMT2AALDH1A1SMN1; SMN2
SCHEMBL24949698 0.72 KDM4E (0.38) KDM4EKMT2AALDH1A1MAPK1SMN1; SMN2
SCHEMBL30206576 0.72 KDM4E (0.38) KDM4EKMT2AALDH1A1MAPK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024133426-A1 METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS AND COMPOUNDS THEREFOR SYNGENTA CROP PROTECTION AG (CH) 2024-06-27 — — WO disclosed
EP-4376616-A1 METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR Syngenta Crop Protection AG (CH) 2024-06-05 — — EP disclosed
CN-117715523-A Methods for controlling diamide-resistant pests and compounds thereof 先正达农作物保护股份公司 2024-03-15 — — CN disclosed
WO-2023006634-A1 METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR SYNGENTA CROP PROTECTION AG (CH) 2023-02-02 — — WO disclosed
US-8658801-B2 Pesticides containing a bicyclic bisamide structure SYNGENTA CROP PROTECTION, LLC (US) 2014-02-25 — — US disclosed
US-8658801-B2 Pesticides containing a bicyclic bisamide structure SYNGENTA CROP PROTECTION, LLC (US) 2014-02-25 — — US disclosed
US-8658801-B2 Pesticides containing a bicyclic bisamide structure SYNGENTA CROP PROTECTION, LLC (US) 2014-02-25 — — US disclosed
US-8598078-B2 Condensed anthran I lami de derivatives as insecticides SYNGENTA CROP PROTECTION, LLC (US) 2013-12-03 — — US disclosed
EP-2178859-B1 CONDENSED ANTHRANILAMIDE DERIVATIVES AS INSECTISIDES SYNGENTA PARTICIPATIONS AG (CH) 2011-12-21 — — EP disclosed
EP-2178859-B1 CONDENSED ANTHRANILAMIDE DERIVATIVES AS INSECTISIDES SYNGENTA PARTICIPATIONS AG (CH) 2011-12-21 — — EP disclosed
US-20090298816-A1 PESTICIDES CONTAINING A BICYCLIC BISAMIDE STRUCTURE SYNGENTA CROP PROTECTION, INC. (US) 2009-12-03 — — US disclosed
US-20090298816-A1 PESTICIDES CONTAINING A BICYCLIC BISAMIDE STRUCTURE SYNGENTA CROP PROTECTION, INC. (US) 2009-12-03 — — US disclosed
US-20090298816-A1 PESTICIDES CONTAINING A BICYCLIC BISAMIDE STRUCTURE SYNGENTA CROP PROTECTION, INC. (US) 2009-12-03 — — US disclosed
EP-1984354-B1 PESTICIDES CONTAINING A BICYCLIC BISAMIDE STRUCTURE SYNGENTA PARTICIPATIONS AG (CH) 2009-08-05 — — EP disclosed
EP-1984354-B1 PESTICIDES CONTAINING A BICYCLIC BISAMIDE STRUCTURE SYNGENTA PARTICIPATIONS AG (CH) 2009-08-05 — — EP disclosed
WO-2009024341-A2 CONDENSED ANTHRAN I LAMI DE DERIVATIVES AS INSECTISIDES SYNGENTA PARTICIPATIONS AG, (CH) 2009-02-26 — — WO disclosed
WO-2009024341-A2 CONDENSED ANTHRAN I LAMI DE DERIVATIVES AS INSECTISIDES SYNGENTA PARTICIPATIONS AG, (CH) 2009-02-26 — — WO disclosed
EP-1984354-A1 PESTICIDES CONTAINING A BICYCLIC BISAMIDE STRUCTURE Syngeta Participations AG (CH) 2008-10-29 — — EP disclosed
WO-2007093402-A1 PESTICIDES CONTAINING A BICYCLIC BISAMIDE STRUCTURE SYNGENTA PARTICIPATIONS AG (CH) 2007-08-23 — — WO disclosed
WO-2007093402-A1 PESTICIDES CONTAINING A BICYCLIC BISAMIDE STRUCTURE SYNGENTA PARTICIPATIONS AG (CH) 2007-08-23 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090298816-A1 PESTICIDES CONTAINING A BICYCLIC BISAMIDE STRUCTURE DDT, ACHE, GAP43 MAPT 124/4885KDM4E 2264/4885KMT2A 2310/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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