SCHEMBL2582880

SCHEMBL2582880

Cc1cc2cn[nH]c2c(C(=O)O)c1N

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.46
KDM4E B2RXH2 2/20 0.38
KMT2A Q03164 1/20 0.38
ALDH1A1 P00352 3/20 0.37
MAPK1 P28482 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
BTK Q06187 5/20 0.36
TNK2 Q07912 2/20 0.36
FGFR1 P11362 2/20 0.36
LRRK2 Q5S007 2/20 0.36
PLK4 O00444 1/20 0.36
CHEK1 O14757 1/20 0.36
AURKA O14965 1/20 0.36
DAPK3 O43293 1/20 0.36
MAP4K4 O95819 1/20 0.36
CSF1R P07333 1/20 0.36
RET P07949 1/20 0.36
PDGFRA P16234 1/20 0.36
LTK P29376 1/20 0.36
KDR P35968 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30206423 1.00 MAPT (0.46) MAPTKDM4EKMT2AALDH1A1MAPK1
SCHEMBL4072321 0.84 TSHR (0.45) MAPTKDM4EKMT2AALDH1A1SMN1; SMN2
SCHEMBL4083786 0.81 NOS1 (0.38) MAPTKDM4EKMT2AALDH1A1BTK
SCHEMBL4071766 0.81 CYP1A2 (0.39) MAPTKDM4EKMT2AALDH1A1MAPK1
SCHEMBL4081049 0.81 CHEK1 (0.34) MAPTBTKTNK2FGFR1LRRK2
SCHEMBL4071770 0.78 LRRK2 (0.38) MAPTKDM4EBTKTNK2FGFR1
SCHEMBL4083790 0.72 CHEK1 (0.46) MAPTKDM4EKMT2AALDH1A1SMN1; SMN2
SCHEMBL551333 0.72 ACACB (0.48) ACACBACACA
SCHEMBL24949698 0.72 KDM4E (0.38) KDM4EKMT2AALDH1A1MAPK1SMN1; SMN2
SCHEMBL30206579 0.72 KDM4E (0.38) KDM4EKMT2AALDH1A1MAPK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024133426-A1 METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS AND COMPOUNDS THEREFOR SYNGENTA CROP PROTECTION AG (CH) 2024-06-27 WO disclosed
EP-4376616-A1 METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR Syngenta Crop Protection AG (CH) 2024-06-05 EP disclosed
CN-117715523-A Methods for controlling diamide-resistant pests and compounds thereof 先正达农作物保护股份公司 2024-03-15 CN disclosed
WO-2023006634-A1 METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR SYNGENTA CROP PROTECTION AG (CH) 2023-02-02 WO disclosed
US-8658801-B2 Pesticides containing a bicyclic bisamide structure SYNGENTA CROP PROTECTION, LLC (US) 2014-02-25 US disclosed
US-8658801-B2 Pesticides containing a bicyclic bisamide structure SYNGENTA CROP PROTECTION, LLC (US) 2014-02-25 US disclosed
US-8658801-B2 Pesticides containing a bicyclic bisamide structure SYNGENTA CROP PROTECTION, LLC (US) 2014-02-25 US disclosed
US-8598078-B2 Condensed anthran I lami de derivatives as insecticides SYNGENTA CROP PROTECTION, LLC (US) 2013-12-03 US disclosed
EP-2178859-B1 CONDENSED ANTHRANILAMIDE DERIVATIVES AS INSECTISIDES SYNGENTA PARTICIPATIONS AG (CH) 2011-12-21 EP disclosed
EP-2178859-B1 CONDENSED ANTHRANILAMIDE DERIVATIVES AS INSECTISIDES SYNGENTA PARTICIPATIONS AG (CH) 2011-12-21 EP disclosed
US-20090298816-A1 PESTICIDES CONTAINING A BICYCLIC BISAMIDE STRUCTURE SYNGENTA CROP PROTECTION, INC. (US) 2009-12-03 US disclosed
US-20090298816-A1 PESTICIDES CONTAINING A BICYCLIC BISAMIDE STRUCTURE SYNGENTA CROP PROTECTION, INC. (US) 2009-12-03 US disclosed
US-20090298816-A1 PESTICIDES CONTAINING A BICYCLIC BISAMIDE STRUCTURE SYNGENTA CROP PROTECTION, INC. (US) 2009-12-03 US disclosed
EP-1984354-B1 PESTICIDES CONTAINING A BICYCLIC BISAMIDE STRUCTURE SYNGENTA PARTICIPATIONS AG (CH) 2009-08-05 EP disclosed
EP-1984354-B1 PESTICIDES CONTAINING A BICYCLIC BISAMIDE STRUCTURE SYNGENTA PARTICIPATIONS AG (CH) 2009-08-05 EP disclosed
WO-2009024341-A2 CONDENSED ANTHRAN I LAMI DE DERIVATIVES AS INSECTISIDES SYNGENTA PARTICIPATIONS AG, (CH) 2009-02-26 WO disclosed
WO-2009024341-A2 CONDENSED ANTHRAN I LAMI DE DERIVATIVES AS INSECTISIDES SYNGENTA PARTICIPATIONS AG, (CH) 2009-02-26 WO disclosed
EP-1984354-A1 PESTICIDES CONTAINING A BICYCLIC BISAMIDE STRUCTURE Syngeta Participations AG (CH) 2008-10-29 EP disclosed
WO-2007093402-A1 PESTICIDES CONTAINING A BICYCLIC BISAMIDE STRUCTURE SYNGENTA PARTICIPATIONS AG (CH) 2007-08-23 WO disclosed
WO-2007093402-A1 PESTICIDES CONTAINING A BICYCLIC BISAMIDE STRUCTURE SYNGENTA PARTICIPATIONS AG (CH) 2007-08-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090298816-A1 PESTICIDES CONTAINING A BICYCLIC BISAMIDE STRUCTURE DDT, ACHE, GAP43 MAPT 124/4885KDM4E 2264/4885KMT2A 2310/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.