Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 2/20 | 0.34 |
| ▸ | DHODH | Q02127 | 5/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30843994 | 1.00 | KDM4E (0.38) | KDM4EALDH1A1MAPK1SMN1; SMN2NUDT1 | |
| SCHEMBL30843991 | 0.84 | ALDH1A1 (0.43) | KDM4EALDH1A1KMT2AGAAHSD17B10 | |
| SCHEMBL24950067 | 0.84 | ALDH1A1 (0.43) | KDM4EALDH1A1KMT2AGAAHSD17B10 | |
| SCHEMBL25083018 | 0.75 | KCNA3 (0.43) | KDM4EALDH1A1NUDT1KMT2AKCNA3 | |
| SCHEMBL24950071 | 0.73 | NUDT1 (0.40) | KDM4EALDH1A1MAPK1SMN1; SMN2NUDT1 | |
| SCHEMBL30843990 | 0.73 | NUDT1 (0.40) | KDM4EALDH1A1MAPK1SMN1; SMN2NUDT1 | |
| SCHEMBL22308308 | 0.73 | NUDT1 (0.42) | KDM4EALDH1A1SMN1; SMN2NUDT1KCNA3 | |
| SCHEMBL4550751 | 0.69 | ESR2 (0.44) | KDM4EALDH1A1SMN1; SMN2NUDT1KMT2A | |
| SCHEMBL1144835 | 0.68 | MAPT (0.42) | KDM4EALDH1A1MAPK1SMN1; SMN2KMT2A | |
| SCHEMBL29185101 | 0.68 | NUDT1 (0.41) | KDM4ESMN1; SMN2NUDT1KMT2AKCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4376616-A1 | METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR | Syngenta Crop Protection AG (CH) | 2024-06-05 | — | — | EP | disclosed |
| CN-117715523-A | Methods for controlling diamide-resistant pests and compounds thereof | 先正达农作物保护股份公司 | 2024-03-15 | — | — | CN | disclosed |
| WO-2023006634-A1 | METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR | SYNGENTA CROP PROTECTION AG (CH) | 2023-02-02 | — | — | WO | disclosed |
| WO-2023006634-A1 | METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR | SYNGENTA CROP PROTECTION AG (CH) | 2023-02-02 | — | — | WO | disclosed |