Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GNAO1 | P09471 | 6/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | PADI1 | Q9ULC6 | 1/20 | 0.33 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.33 |
| ▸ | GNAI3 | P08754 | 5/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 5/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.32 |
| ▸ | NCF1 | P14598 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.30 |
| ▸ | PHGDH | O43175 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18780643 | 0.78 | GNAO1 (0.34) | GNAO1GNAI3GNAI1NCF1 | |
| SCHEMBL6613727 | 0.74 | SMYD3 (0.37) | SMN1; SMN2GNAO1SMYD3 | |
| SCHEMBL21038372 | 0.72 | GNAO1 (0.36) | SMN1; SMN2GNAO1GNAI3GNAI1SMYD3 | |
| SCHEMBL13600026 | 0.72 | NCF1 (0.41) | GNAO1GNAI3GNAI1NCF1 | |
| SCHEMBL19534541 | 0.72 | NCF1 (0.41) | GNAO1GNAI3GNAI1NCF1 | |
| SCHEMBL21911443 | 0.70 | GNAO1 (0.34) | GNAO1GNAI3GNAI1SMYD3 | |
| SCHEMBL18212448 | 0.70 | MEN1 (0.41) | CHRM5POLBSIGMAR1SMYD3 | |
| SCHEMBL18212445 | 0.70 | MEN1 (0.41) | CHRM5POLBSIGMAR1SMYD3 | |
| SCHEMBL13833229 | 0.70 | SMN1; SMN2 (0.47) | SMN1; SMN2RAD52CHRM5CHRM3PADI1 | |
| SCHEMBL713548 | 0.70 | SMN1; SMN2 (0.47) | SMN1; SMN2RAD52CHRM5CHRM3PADI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4122925-A1 | PROTEOLYSIS REGULATOR AND METHOD FOR USING SAME | Medshine Discovery Inc. (CN) | 2023-01-25 | — | — | EP | disclosed |