SCHEMBL24951966

SCHEMBL24951966

CC(C)c1ccc(N2C(=O)CC(S)C2=O)c(F)c1F

nearest known ligand 0.47

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ ADAM17 P78536 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24951952 0.88 ADAM17 (0.43) ADAM17
SCHEMBL24018625 0.81 ADAM17 (0.44) ADAM17
SCHEMBL20621728 0.78 ADAM17 (0.42) ADAM17
SCHEMBL24018572 0.75 ADAM17 (0.46) ADAM17
SCHEMBL20621770 0.72 ADAM17 (0.43) ADAM17
SCHEMBL24018590 0.71 ADAM17 (0.44) ADAM17
SCHEMBL24952371 0.71 ADAM17 (0.51) ADAM17
SCHEMBL20622025 0.69 ADAM17 (0.42) ADAM17
SCHEMBL24018510 0.66 ADAM17 (0.55) ADAM17
SCHEMBL24951701 0.65 ADAM17 (0.39) ADAM17

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230023537-A1 DELIVERY SYSTEMS FOR CONTROLLED DRUG RELEASE LADRX CORPORATION 2023-01-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230023537-A1 DELIVERY SYSTEMS FOR CONTROLLED DRUG RELEASE ABCB11, SLC10A1, SLC5A1 ADAM17 1186/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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