Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20180680 | 0.86 | HTT (0.34) | GPBAR1ALDH1A1BACE1BACE2 | |
| SCHEMBL20180664 | 0.86 | HTT (0.34) | GPBAR1ALDH1A1BACE1BACE2 | |
| SCHEMBL20180516 | 0.86 | HTT (0.34) | GPBAR1ALDH1A1BACE1BACE2 | |
| SCHEMBL23369279 | 0.86 | HTT (0.34) | GPBAR1ALDH1A1BACE1BACE2 | |
| SCHEMBL12013341 | 0.86 | HTT (0.34) | GPBAR1ALDH1A1BACE1BACE2 | |
| SCHEMBL19533069 | 0.86 | HTT (0.34) | GPBAR1ALDH1A1BACE1BACE2 | |
| SCHEMBL19245754 | 0.85 | GPBAR1 (0.31) | GPBAR1ALDH1A1BACE1BACE2 | |
| SCHEMBL21126773 | 0.85 | GPBAR1 (0.31) | GPBAR1ALDH1A1BACE1BACE2 | |
| SCHEMBL17570992 | 0.85 | ALDH1A1 (0.33) | GPBAR1ALDH1A1BACE1BACE2 | |
| SCHEMBL20056975 | 0.85 | ALDH1A1 (0.38) | ALDH1A1BACE1BACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023000131-A1 | ANTIBODY DRUG CONJUGATE LOADED WITH DOUBLE TOXINS AND APPLICATION THEREOF | 烟台迈百瑞国际生物医药股份有限公司 | 2023-01-26 | — | — | WO | disclosed |