Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20180680 | 1.00 | HTT (0.34) | HTTGPBAR1ALDH1A1FKBP1ABACE1 | |
| SCHEMBL23369279 | 1.00 | HTT (0.34) | HTTGPBAR1ALDH1A1FKBP1ABACE1 | |
| SCHEMBL12013341 | 1.00 | HTT (0.34) | HTTGPBAR1ALDH1A1FKBP1ABACE1 | |
| SCHEMBL20180664 | 1.00 | HTT (0.34) | HTTGPBAR1ALDH1A1FKBP1ABACE1 | |
| SCHEMBL19533069 | 1.00 | HTT (0.34) | HTTGPBAR1ALDH1A1FKBP1ABACE1 | |
| SCHEMBL26755735 | 0.87 | ACHE (0.32) | ALDH1A1FKBP1A | |
| SCHEMBL19245754 | 0.86 | GPBAR1 (0.31) | GPBAR1ALDH1A1BACE1BACE2 | |
| SCHEMBL21126773 | 0.86 | GPBAR1 (0.31) | GPBAR1ALDH1A1BACE1BACE2 | |
| SCHEMBL17570992 | 0.86 | ALDH1A1 (0.33) | GPBAR1ALDH1A1BACE1BACE2 | |
| SCHEMBL24952144 | 0.86 | GPBAR1 (0.31) | GPBAR1ALDH1A1BACE1BACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022087243-A1 | ANTI-FGFR2 ANTIBODIES AND METHODS OF USE THEREOF | REGENERON PHARMACEUTICALS, INC. (US) | 2022-04-28 | — | — | WO | disclosed |
| WO-2019217591-A1 | ANTI-MSR1 ANTIBODIES AND METHODS OF USE THEREOF | REGENERON PHARMACEUTICALS, INC. (US) | 2019-11-14 | — | — | WO | disclosed |
| WO-2018093866-A1 | ANTI-MET ANTIBODIES, BISPECIFIC ANTIGEN BINDING MOLECULES THAT BIND MET, AND METHODS OF USE THEREOF | REGENERON PHARMACEUTICALS, INC. (US) | 2018-05-24 | — | — | WO | disclosed |