⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10615892 | 0.67 | — | — | |
| SCHEMBL9421787 | 0.61 | — | — | |
| SCHEMBL49524 | 0.61 | — | — | |
| SCHEMBL31388943 | 0.61 | — | — | |
| SCHEMBL4607418 | 0.61 | — | — | |
| SCHEMBL535839 | 0.61 | — | — | |
| SCHEMBL789877 | 0.55 | — | — | |
| SCHEMBL10824466 | 0.55 | — | — | |
| SCHEMBL9234557 | 0.55 | — | — | |
| SCHEMBL1895030 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112110862-B | Preparation method and application of 1,4,5, 6-tetrahydro-5-hydroxypyrimidine compound and hydrochloride thereof | 重庆华邦制药有限公司 | 2023-10-17 | — | — | CN | claimed |
| CN-112110862-A | Preparation method and application of 1,4,5, 6-tetrahydro-5-hydroxypyrimidine compound and hydrochloride thereof | 重庆华邦制药有限公司 | 2020-12-22 | — | — | CN | claimed |
| CN-104529740-A | Tricyclic diterpenoid derivative and preparation method as well as application of tricyclic diterpenoid derivative in preparation of neuroprotective drugs | UNIV EAST CHINA NORMAL | 2015-04-22 | — | — | CN | claimed |
| CN-101747461-A | Polymer containing hydroxystyrene on side group, preparation method and application thereof | BEIJING INST PETROCHEM TECH | 2010-06-23 | — | — | CN | claimed |
| CN-112110862-B | Preparation method and application of 1,4,5, 6-tetrahydro-5-hydroxypyrimidine compound and hydrochloride thereof | 重庆华邦制药有限公司 | 2023-10-17 | — | — | CN | disclosed |
| CN-110963956-B | Preparation method of amphetamine type novel alkaloid | 成都中医药大学 | 2023-05-16 | — | — | CN | disclosed |
| CN-112898827-B | Ultraviolet curing packaging ink based on silicon-oxygen side chain-containing two-dimensional acrylate monomer and use method and application thereof | 西安思摩威新材料有限公司 | 2022-10-18 | — | — | CN | disclosed |
| CN-112110862-A | Preparation method and application of 1,4,5, 6-tetrahydro-5-hydroxypyrimidine compound and hydrochloride thereof | 重庆华邦制药有限公司 | 2020-12-22 | — | — | CN | disclosed |
| CN-110963956-A | Preparation method of new phenylalamine alkaloid | 成都中医药大学 | 2020-04-07 | — | — | CN | disclosed |
| CN-105111440-B | A kind of continuous environment-friendly preparation process of high-temperature resistant coating methyl phenyl silicone resin | 唐山三友硅业有限责任公司 | 2018-10-12 | — | — | CN | disclosed |
| CN-104529740-B | Tricyclic diterpene derivative and its preparation method and in the application prepared in nerve protection medicine | EAST CHINA NORMAL UNIVERSITY (CN) | 2016-06-01 | — | — | CN | disclosed |
| CN-104529740-A | Tricyclic diterpenoid derivative and preparation method as well as application of tricyclic diterpenoid derivative in preparation of neuroprotective drugs | UNIV EAST CHINA NORMAL | 2015-04-22 | — | — | CN | disclosed |
| CN-1248222-A | Neutral aged hydrophobic organosilicate-modified silica gels | DOW CORNING (US) | 2000-03-22 | — | — | CN | disclosed |
| CN-1248223-A | Method for preparing hydrophobic organosilicate-modified silica gel under neutral condition | DOW CORNING (US) | 2000-03-22 | — | — | CN | disclosed |
| CN-1248220-A | Neutral-aged hydrophobic silica gels with reduced surface area | DOW CORNING (US) | 2000-03-22 | — | — | CN | disclosed |
| CN-1248221-A | Process for making hydrophobic silica gels with reduced surface area under neutral conditions | DOW CORNING (US) | 2000-03-22 | — | — | CN | disclosed |
| CN-1248226-A | Hydrophobic silica gels with reduced surface area | DOW CORNING (US) | 2000-03-22 | — | — | CN | disclosed |
| EP-0082079-B1 | PROCESS FOR ETCHING AND DEACTIVATING GLASS CAPILLARIES FOR CHROMATOGRAPHY | THE DOW CHEMICAL COMPANY (US) | 1986-04-16 | — | — | EP | disclosed |
| EP-0082079-A1 | Process for etching and deactivating glass capillaries for chromatography | THE DOW CHEMICAL COMPANY (US) | 1983-06-22 | — | — | EP | disclosed |
| US-4376641-A | Coated capillary chromatographic column | THE DOW CHEMICAL COMPANY (US) | 1983-03-15 | — | — | US | disclosed |