Iodide

Iodide

SCHEMBL2495412

C=Cc1cccc2c1C(=O)NC2=O.I

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG

The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 2/20 0.45
KDM4E B2RXH2 3/20 0.42
ALDH1A1 P00352 3/20 0.42
HPGD P15428 2/20 0.42
HSD17B10 Q99714 2/20 0.42
GAA P10253 1/20 0.42
PARP1 P09874 6/20 0.42
CASP3 P42574 4/20 0.39
CASP7 P55210 2/20 0.39
CASP2 P42575 1/20 0.39
CASP6 P55212 1/20 0.39
CASP8 Q14790 1/20 0.39
NPSR1 Q6W5P4 2/20 0.36
MEN1 O00255 1/20 0.36
RGS12 O14924 1/20 0.36
USP2 O75604 1/20 0.36
CYP1A2 P05177 1/20 0.36
POLB P06746 1/20 0.36
CYP3A4 P08684 1/20 0.36
MAPT P10636 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL626418 0.98 GSK3B (0.46) GSK3BKDM4EALDH1A1HPGDHSD17B10
Acrylic Acid SCHEMBL11605192 0.89 KDM4E (0.44) GSK3BKDM4EALDH1A1HPGDHSD17B10
SCHEMBL19245114 0.83 GSK3B (0.39) GSK3BKDM4EALDH1A1HPGDHSD17B10
SCHEMBL12430646 0.83 GSK3B (0.39) GSK3BKDM4EALDH1A1HPGDHSD17B10
SCHEMBL31229225 0.81 GSK3B (0.48) GSK3BKDM4EALDH1A1HPGDHSD17B10
SCHEMBL1627401 0.81 GSK3B (0.48) GSK3BKDM4EALDH1A1HPGDHSD17B10
SCHEMBL28735098 0.81 GSK3B (0.41) GSK3BKDM4EALDH1A1HPGDHSD17B10
SCHEMBL579203 0.79 GSK3B (0.46) GSK3BKDM4EALDH1A1HPGDHSD17B10
SCHEMBL8577337 0.76 KDM4E (0.45) GSK3BKDM4EALDH1A1HPGDHSD17B10
SCHEMBL16754925 0.75 GSK3B (0.62) GSK3BKDM4EALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2371398-B1 MEDICAL SUPPLIES AND METHOD OF PRODUCING THE SAME PROSTEC CO LTD (JP) 2013-05-15 EP claimed
US-20240207482-A1 SURFACE TREATMENT METHODS FOR CEMENTLESS IMPLANTABLE MEDICAL DEVICES DURAHIP, LLC 2024-06-27 US disclosed
EP-3586882-B1 ANTIBACTERIAL BIOLOGICAL IMPLANT PROSTEC CO LTD (JP) 2023-02-22 EP disclosed
EP-3981444-A1 METHODS OF MODIFYING THE POROUS SURFACE OF IMPLANTS Biomet Manufacturing, LLC (US) 2022-04-13 EP disclosed
EP-3586883-B1 METHOD FOR PRODUCING ANTIBACTERIAL BIOLOGICAL IMPLANT PROSTEC CO LTD (JP) 2021-11-17 EP disclosed
US-20210186703-A1 METHODS OF MODIFYING THE POROUS SURFACE OF IMPLANTS BIOMET MFG LLC (US) 2021-06-24 US disclosed
US-10980914-B2 Antibacterial biological implant PROSTEC CO., LTD. (JP) 2021-04-20 US disclosed
EP-3391915-B1 METHODS OF MODIFYING THE POROUS SURFACE OF IMPLANTS BIOMET MFG LLC (US) 2021-04-14 EP disclosed
US-10940234-B2 Method for producing antibacterial biological implant PROSTEC CO., LTD. (JP) 2021-03-09 US disclosed
US-10893944-B2 Methods of modifying the porous surface of implants BIOMET MANUFACTURING, LLC (US) 2021-01-19 US disclosed
US-10668187-B2 Medical supplies and method of producing the same PROSTEC CO., LTD. (JP) 2020-06-02 US disclosed
US-20200030487-A1 METHOD FOR PRODUCING ANTIBACTERIAL BIOLOGICAL IMPLANT PROSTEC CO., LTD. (JP) 2020-01-30 US disclosed
EP-3391915-A2 METHODS OF MODIFYING THE POROUS SURFACE OF IMPLANTS Biomet Manufacturing, LLC (US) 2018-10-24 EP disclosed
US-20180280143-A1 METHODS OF MODIFYING THE POROUS SURFACE OF IMPLANTS BIOMET MANUFACTURING, LLC 2018-10-04 US disclosed
US-20180243483-A1 MEDICAL SUPPLIES AND METHOD OF PRODUCING THE SAME PROSTEC CO LTD (JP) 2018-08-30 US disclosed
US-9889231-B2 Medical supplies and method of producing the same PROSTEC CO., LTD. (JP) 2018-02-13 US disclosed
US-20130240365-A1 MEDICAL SUPPLIES AND METHOD OF PRODUCING THE SAME PROSTEC CO., LTD. (JP) 2013-09-19 US disclosed
EP-2371398-B1 MEDICAL SUPPLIES AND METHOD OF PRODUCING THE SAME PROSTEC CO LTD (JP) 2013-05-15 EP disclosed
US-20110313539-A1 MEDICAL SUPPLIES AND METHOD OF PRODUCING THE SAME PROSTEC CO., LTD. (JP) 2011-12-22 US disclosed
EP-2371398-A1 MEDICAL PART AND MANUFACTURING METHOD THEREFOR Prostec Co., Ltd. (JP) 2011-10-05 EP disclosed