Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | GSK3B | P49841 | 2/20 | 0.43 |
| ▸ | PARP1 | P09874 | 5/20 | 0.41 |
| ▸ | CASP3 | P42574 | 5/20 | 0.40 |
| ▸ | CASP7 | P55210 | 2/20 | 0.38 |
| ▸ | CASP2 | P42575 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | RGS12 | O14924 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7552794 | 0.81 | KDM4E (0.42) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL7693227 | 0.81 | KDM4E (0.42) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL1627401 | 0.79 | GSK3B (0.48) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL31229225 | 0.79 | GSK3B (0.48) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL28735098 | 0.79 | GSK3B (0.41) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL9333299 | 0.79 | KDM4E (0.47) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL579203 | 0.78 | GSK3B (0.46) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL626418 | 0.78 | GSK3B (0.46) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL7912431 | 0.77 | KDM4E (0.48) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| Iodide SCHEMBL2495412 | 0.76 | GSK3B (0.45) | KDM4EALDH1A1HPGDHSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998018833-A1 | POLY(VINYL AMINE) ANALOGS | UNIVERSITY OF MASSACHUSETTS (US) | 1998-05-07 | — | — | WO | disclosed |