Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.46 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.44 |
| ▸ | BID | P55957 | 3/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.41 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.41 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.41 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.41 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27397512 | 0.98 | GPR84 (0.49) | GPR84LIPGNR1H2NR1H3BID | |
| SCHEMBL28243243 | 0.98 | GPR84 (0.49) | GPR84LIPGNR1H2NR1H3BID | |
| SCHEMBL5166986 | 0.98 | GPR84 (0.49) | GPR84LIPGNR1H2NR1H3BID | |
| SCHEMBL14974903 | 0.98 | GPR84 (0.49) | GPR84LIPGNR1H2NR1H3BID | |
| SCHEMBL10767574 | 0.98 | GPR84 (0.49) | GPR84LIPGNR1H2NR1H3BID | |
| SCHEMBL10764266 | 0.98 | GPR84 (0.49) | GPR84LIPGNR1H2NR1H3BID | |
| SCHEMBL10692239 | 0.94 | DAO (0.41) | GPR84LIPGNR1H2NR1H3BID | |
| SCHEMBL9234355 | 0.88 | DAO (0.45) | GPR84LIPGNR1H2NR1H3BID | |
| SCHEMBL174911 | 0.86 | KDM4E (0.44) | GPR84MCL1DAOAURKAAURKB | |
| SCHEMBL28003330 | 0.81 | BID (0.44) | GPR84BIDMCL1BCL2L1BAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106905230-A | A kind of preparation method of aryl pyridinones compound | 周晓芳 | 2017-06-30 | — | — | CN | claimed |
| CN-104923165-B | A kind of derivant based on aryl pyridones molecular skeleton and its application in preparing hydrargyrum trapping agent | 广东工业大学 | 2017-03-01 | — | — | CN | claimed |
| CN-104923165-A | Derivative based on aromatic pyridone molecular skeleton, and application thereof in preparing mercury capturing agent | UNIV GUANGDONG TECHNOLOGY | 2015-09-23 | — | — | CN | claimed |
| CN-102786467-A | N-substitutional aryl pyridine ketone compound as well as preparation method and application of N-substitutional aryl pyridine ketone compound | ZHEJIANG ACADEMY MEDICAL SCI | 2012-11-21 | — | — | CN | claimed |
| CN-113897631-B | Method for electrochemical synthesis of pyridin-2-one derivatives | 昆明学院 | 2023-05-09 | — | — | CN | disclosed |
| CN-113897631-A | Method for electrochemically synthesizing pyridine-2-one derivatives | 昆明学院 | 2022-01-07 | — | — | CN | disclosed |
| CN-110256405-A | 5- alkyl-N- substituted aryl Pyridione derivatives and its preparation method and application | 四川国康药业有限公司 | 2019-09-20 | — | — | CN | disclosed |
| CN-106397408-B | 5- methyl -2 (1H) Pyridione derivatives and its preparation method and application | 四川大学 | 2019-04-02 | — | — | CN | disclosed |
| CN-105793251-B | Heteroaryl pyridines ketone with electrophilic functionality and azepine-pyridinone compounds | 豪夫迈·罗氏有限公司 | 2018-10-12 | — | — | CN | disclosed |
| CN-107922431-A | HPK1 inhibitors and methods of use thereof | 大学健康网络 | 2018-04-17 | — | — | CN | disclosed |
| CN-105175326-B | 5 methyl 2 (1H) Pyridione derivatives and its production and use | 四川国康药业有限公司 | 2018-02-27 | — | — | CN | disclosed |
| CN-105085383-B | 5 methyl 2 (1H) Pyridione derivatives and its production and use | 四川大学 | 2017-09-01 | — | — | CN | disclosed |
| US-4866078-A | Phenyl pyridones and insectidal use thereof | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-09-12 | — | — | US | disclosed |
| EP-0259048-A2 | Chemical compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-03-09 | — | — | EP | disclosed |
| US-4725607-A | MITICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-02-16 | — | — | US | disclosed |
| US-4725607-A | MITICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-02-16 | — | — | US | disclosed |
| EP-0216541-A1 | Aryl pyridones | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-04-01 | — | — | EP | disclosed |
| EP-0216541-A1 | Aryl pyridones | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-04-01 | — | — | EP | disclosed |
| CN-86106734-A | ARYL PYRIDONES | — | 1987-04-01 | — | — | CN | disclosed |
| CN-86106734-A | ARYL PYRIDONES | — | 1987-04-01 | — | — | CN | disclosed |