SCHEMBL5166986

SCHEMBL5166986

CCCCCCCCCCCCc1ccc[nH]c1=O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 2/20 0.49
LIPG Q9Y5X9 1/20 0.47
NR1H2 P55055 1/20 0.46
NR1H3 Q13133 1/20 0.46
BID P55957 3/20 0.44
MCL1 Q07820 3/20 0.44
PPARA Q07869 3/20 0.44
BCL2L1 Q07817 2/20 0.44
BAK1 Q16611 2/20 0.44
KAT8 Q9H7Z6 2/20 0.44
PPARG P37231 2/20 0.44
EP300 Q09472 1/20 0.44
KAT2A Q92830 1/20 0.44
KAT2B Q92831 1/20 0.44
KAT5 Q92993 1/20 0.44
SAE1 Q9UBE0 1/20 0.44
THRA P10827 1/20 0.40
THRB P10828 1/20 0.40
KDM4E B2RXH2 1/20 0.40
ALDH1A1 P00352 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28243243 1.00 GPR84 (0.49) GPR84LIPGNR1H2NR1H3BID
SCHEMBL10767574 1.00 GPR84 (0.49) GPR84LIPGNR1H2NR1H3BID
SCHEMBL27397512 1.00 GPR84 (0.49) GPR84LIPGNR1H2NR1H3BID
SCHEMBL10764266 1.00 GPR84 (0.49) GPR84LIPGNR1H2NR1H3BID
SCHEMBL14974903 1.00 GPR84 (0.49) GPR84LIPGNR1H2NR1H3BID
SCHEMBL2495417 0.98 GPR84 (0.46) GPR84LIPGNR1H2NR1H3BID
SCHEMBL10692239 0.93 DAO (0.41) GPR84LIPGNR1H2NR1H3BID
SCHEMBL9234355 0.91 DAO (0.45) GPR84LIPGNR1H2NR1H3BID
SCHEMBL174911 0.85 KDM4E (0.44) GPR84MCL1THRBKDM4EALDH1A1
SCHEMBL28003330 0.83 BID (0.44) GPR84BIDMCL1PPARABCL2L1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1375610-B1 Phase change inks containing dimeric azo pyridone colorants XEROX CORP (US) 2007-04-04 EP disclosed
EP-1375599-B1 Dimeric azo pyridone colorants XEROX CORP (US) 2006-10-04 EP disclosed
CN-1702545-A Method for forming temporary image XEROX CORP (US) 2005-11-30 CN disclosed
CN-1702546-A Method for forming temporary image XEROX CORP (US) 2005-11-30 CN disclosed
US-6713614-B2 PHASE CHANGE INKS XEROX CORPORATION 2004-03-30 US disclosed
US-6696552-B2 AMIDATION BETWEEN PRIMARY AMINE AND ESTER HAVING ELECTRON WITHDRAWING FUNCTIONALITY; CYCLIZATION WITH KETO ESTER XEROX CORPORATION 2004-02-24 US disclosed
US-20040010058-A1 DIMERIC AZO PYRIDONE COLORANTS XEROX CORPORATION 2004-01-15 US disclosed
US-20040006234-A1 PROCESS FOR PREPARING SUBSTITUTED PYRIDONE COMPOUNDS XEROX CORPORATION 2004-01-08 US disclosed
EP-1375610-A1 Phase change inks containing dimeric azo pyridone colorants Xerox Corporation (US) 2004-01-02 EP disclosed
EP-1375599-A1 Dimeric azo pyridone colorants Xerox Corporation (US) 2004-01-02 EP disclosed
US-6663703-B1 Nonsettling hot melt color materials and carriers comprising stearyl stearamide, the reaction product of dimer acid, ethylene diamine and stearic acid or mixtures, used in ink jets printers, having colorfastness, heat and photostability XEROX CORPORATION 2003-12-16 US disclosed
US-6576747-B1 Reacting alkylenediol and isatoic anhydride in presence of 1,4-diazabicyclo(2.2.2)octane and/or N,N,N*,N*-tetramethylenediamine; heating, decyclization, salt formation XEROX CORPORATION 2003-06-10 US disclosed
US-6576748-B1 Diazotizing dianiline compound; salt formation, coupling, desalting; reaction with pyridone or dipyridone compound XEROX CORPORATION 2003-06-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040006234-A1 PROCESS FOR PREPARING SUBSTITUTED PYRIDONE COMPOUNDS PDXK, DPYD, RRM2B GPR84 4329/4885LIPG 4540/4885NR1H2 3109/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.