Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2228600 | 0.86 | ALDH1A1 (0.40) | KDM4EPKMALDH1A1MEN1KMT2A | |
| SCHEMBL13347183 | 0.83 | KDM4E (0.34) | KDM4EPKMALDH1A1 | |
| SCHEMBL16233604 | 0.81 | ALDH1A1 (0.35) | KDM4EPKMALDH1A1MEN1KMT2A | |
| SCHEMBL16770070 | 0.79 | KDM4E (0.36) | KDM4EPKM | |
| SCHEMBL23570076 | 0.72 | LMNA (0.32) | KDM4EPKM | |
| SCHEMBL14609318 | 0.71 | KDM4E (0.46) | KDM4EPKM | |
| SCHEMBL20443544 | 0.71 | KDM4E (0.32) | KDM4EPKM | |
| SCHEMBL14355438 | 0.71 | — | — | |
| SCHEMBL13327397 | 0.70 | — | — | |
| SCHEMBL16233648 | 0.70 | MEN1 (0.34) | KDM4EPKMALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023007185-A1 | IMIDAZOLE ORGANIC COMPOUNDS AND THEIR USE AGAINST INFLAMMATORY BOWEL DISEASE | Benevolentai Cambridge Limited (GB) | 2023-02-02 | — | — | WO | disclosed |