Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 7/20 | 0.46 |
| ▸ | AURKA | O14965 | 5/20 | 0.43 |
| ▸ | AURKC | Q9UQB9 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.39 |
| ▸ | MTOR | P42345 | 2/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.38 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24955640 | 0.90 | PIK3CA (0.47) | PIK3CAALDH1A1SMN1; SMN2PDE10AMTOR | |
| SCHEMBL30202160 | 0.87 | SYK (0.35) | PIK3CAAURKAPDE10ACYP2E1CYP2A6 | |
| SCHEMBL24955686 | 0.77 | PDE10A (0.38) | PIK3CAPDE10ALRRK2 | |
| SCHEMBL30202390 | 0.77 | PDE10A (0.38) | PIK3CAPDE10ALRRK2 | |
| SCHEMBL30203054 | 0.77 | CNR2 (0.38) | PIK3CAPDE10A | |
| SCHEMBL30202168 | 0.77 | MTOR (0.49) | PIK3CAPDE10AMTORPIK3CD | |
| SCHEMBL30202248 | 0.77 | MTOR (0.49) | PIK3CAPDE10AMTORPIK3CD | |
| SCHEMBL24955629 | 0.76 | PIK3CA (0.39) | PIK3CAALDH1A1SMN1; SMN2PDE10APIK3CG | |
| SCHEMBL24955834 | 0.75 | MEN1 (0.43) | PIK3CAALDH1A1HTTSMN1; SMN2PDE10A | |
| SCHEMBL31106989 | 0.74 | MTOR (0.43) | PIK3CAMTORPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023007185-A1 | IMIDAZOLE ORGANIC COMPOUNDS AND THEIR USE AGAINST INFLAMMATORY BOWEL DISEASE | Benevolentai Cambridge Limited (GB) | 2023-02-02 | — | — | WO | disclosed |