Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 8/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.35 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | TSPO | P30536 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30202390 | 1.00 | PDE10A (0.38) | PDE10AADORA1MAP3K12PIK3CAADORA3 | |
| SCHEMBL24955640 | 0.86 | PIK3CA (0.47) | PDE10AADORA1PIK3CALRRK2 | |
| SCHEMBL31106972 | 0.85 | DGAT1 (0.38) | — | |
| SCHEMBL24955726 | 0.85 | DGAT1 (0.38) | — | |
| SCHEMBL24956765 | 0.84 | LRRK2 (0.34) | ADORA1MAP3K12PIK3CAADORA3TSPO | |
| SCHEMBL30202293 | 0.84 | LRRK2 (0.34) | ADORA1MAP3K12PIK3CAADORA3TSPO | |
| SCHEMBL30203054 | 0.84 | CNR2 (0.38) | PDE10AADORA1MAP3K12PIK3CA | |
| SCHEMBL30202075 | 0.83 | PDE10A (0.37) | PDE10APIK3CACHRNB2CHRNA7CHRNA4 | |
| SCHEMBL30202168 | 0.81 | MTOR (0.49) | PDE10APIK3CA | |
| SCHEMBL30202248 | 0.81 | MTOR (0.49) | PDE10APIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023007185-A1 | IMIDAZOLE ORGANIC COMPOUNDS AND THEIR USE AGAINST INFLAMMATORY BOWEL DISEASE | Benevolentai Cambridge Limited (GB) | 2023-02-02 | — | — | WO | disclosed |