Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | GPR183 | P32249 | 1/20 | 0.54 |
| ▸ | LDHA | P00338 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | GABRD | O14764 | 1/20 | 0.52 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.52 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.52 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.52 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.52 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.52 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.52 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12835048 | 0.86 | LDHA (0.63) | HPGDGPR183LDHAL3MBTL1HTT | |
| SCHEMBL7130857 | 0.85 | HPGD (0.83) | HPGDGPR183L3MBTL1HTTGABRD | |
| SCHEMBL14238822 | 0.85 | HPGD (0.83) | HPGDGPR183L3MBTL1HTTGABRD | |
| SCHEMBL13246374 | 0.84 | HPGD (0.68) | HPGDLDHAL3MBTL1HTTGABRD | |
| SCHEMBL12286133 | 0.82 | HPGD (0.64) | HPGDLDHAL3MBTL1HTTGABRD | |
| SCHEMBL12630845 | 0.81 | HPGD (0.62) | HPGDGPR183LDHAL3MBTL1HTT | |
| SCHEMBL8916079 | 0.80 | TSHR (0.82) | L3MBTL1HTTMEN1LMNAKMT2A | |
| SCHEMBL12563716 | 0.79 | HPGD (0.73) | HPGDGPR183L3MBTL1HTTGABRD | |
| SCHEMBL8360507 | 0.79 | HPGD (0.73) | HPGDL3MBTL1HTTGABRDGABRA1 | |
| SCHEMBL2667152 | 0.79 | HPGD (0.90) | HPGDL3MBTL1HTTGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023001108-A1 | PREPARATION OF HISTONE DEACETYLASE INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 成都赜灵生物医药科技有限公司 | 2023-01-26 | — | — | WO | disclosed |