SCHEMBL28434162

SCHEMBL28434162

Cc1ccccc1C(CO)N(CCO)c1ccccc1C

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.35
MAPT P10636 1/20 0.35
PKM P14618 1/20 0.35
HTT P42858 1/20 0.35
MCL1 Q07820 1/20 0.35
ESR1 P03372 1/20 0.34
ACP3 P15309 1/20 0.34
CYP3A4 P08684 3/20 0.33
CYP2D6 P10635 2/20 0.33
SLC6A2 P23975 2/20 0.33
SLC6A4 P31645 2/20 0.33
OPRM1 P35372 2/20 0.33
SLC22A2 O15244 1/20 0.33
SLC22A1 O15245 1/20 0.33
GRIN2D O15399 1/20 0.33
GRIN3B O60391 1/20 0.33
CHRM2 P08172 1/20 0.33
CHRM4 P08173 1/20 0.33
CHRM5 P08912 1/20 0.33
ADRA2A P08913 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10777362 0.76 MAPT (0.36) GAAMAPTPKMHTTMCL1
SCHEMBL2495689 0.76 SLC6A2 (0.42) CYP3A4CYP2D6SLC6A2SLC6A4OPRM1
SCHEMBL29421638 0.70 ALDH1A1 (0.47) GAAMAPTPKMHTTMCL1
SCHEMBL94000 0.70 ALDH1A1 (0.47) GAAMAPTPKMHTTMCL1
SCHEMBL11702654 0.69 ALDH1A1 (0.45) GAAMAPTCYP3A4SLC6A2SLC6A4
SCHEMBL6481460 0.68 ESR1 (0.46) GAAESR1ACP3CYP3A4CYP2D6
SCHEMBL2543874 0.68 ESR1 (0.46) GAAESR1ACP3CYP3A4CYP2D6
SCHEMBL31376576 0.68 ESR1 (0.46) GAAESR1ACP3CYP3A4CYP2D6
SCHEMBL17660054 0.68 ESR1 (0.46) GAAESR1ACP3CYP3A4CYP2D6
SCHEMBL10963146 0.68 KDM4E (0.50) GAAMAPTPKMHTTMCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115777010-A Low friction and low traction lubricant composition useful for dry clutch motorcycles 埃克森美孚技术与工程公司 2023-03-10 CN disclosed
CN-114838515-A Refrigeration cycle device 大金工业株式会社 2022-08-02 CN disclosed
CN-114656934-A Refrigerant cycle device 大金工业株式会社 2022-06-24 CN disclosed
CN-114475162-A Refrigeration cycle device for automobile 大金工业株式会社 2022-05-13 CN disclosed
CN-113366274-A Air conditioner in warehouse 大金工业株式会社 2021-09-07 CN disclosed
CN-112673075-A Refrigeration cycle device 大金工业株式会社 2021-04-16 CN disclosed
CN-112673074-A Refrigeration cycle device for automobile 大金工业株式会社 2021-04-16 CN disclosed
CN-112654688-A Refrigerant cycle device 大金工业株式会社 2021-04-13 CN disclosed
CN-111511874-A Refrigeration cycle device 大金工业株式会社 2020-08-07 CN disclosed
CN-111492033-A Refrigeration cycle device 大金工业株式会社 2020-08-04 CN disclosed
CN-111479910-A Refrigerating machine oil for refrigerant or refrigerant composition, method for using refrigerating machine oil, and use as refrigerating machine oil 大金工业株式会社 2020-07-31 CN disclosed