SCHEMBL249578

SCHEMBL249578

O=C(O)c1ccc(F)c2ccccc12

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A1 P22736 1/20 0.52
NR4A2 P43354 1/20 0.52
NR4A3 Q92570 1/20 0.52
CXCR5 P32302 1/20 0.51
WDR5 P61964 1/20 0.48
ALDH1A1 P00352 1/20 0.48
ALOX15 P16050 1/20 0.48
KDM4E B2RXH2 3/20 0.47
LDHA P00338 1/20 0.47
CYP2C9 P11712 1/20 0.47
HPGD P15428 1/20 0.47
TSHR P16473 1/20 0.47
ALOX12 P18054 1/20 0.47
ATIC P31939 1/20 0.47
HSD17B10 Q99714 1/20 0.47
ALB P02768 1/20 0.45
CNR1 P21554 2/20 0.44
CNR2 P34972 2/20 0.44
LMNA P02545 1/20 0.44
AKR1C2 P52895 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2754168 0.87 ALB (0.61) NR4A1NR4A2NR4A3ALDH1A1ALOX15
SCHEMBL28798 0.86 NR4A1 (0.65) NR4A1NR4A2NR4A3WDR5ALDH1A1
SCHEMBL30838413 0.86 NR4A1 (0.65) NR4A1NR4A2NR4A3WDR5ALDH1A1
SCHEMBL29406630 0.86 NR4A1 (0.65) NR4A1NR4A2NR4A3WDR5ALDH1A1
SCHEMBL30838412 0.86 NR4A1 (0.65) NR4A1NR4A2NR4A3WDR5ALDH1A1
Hydrochloric Acid SCHEMBL3358028 0.84 NR4A1 (0.62) NR4A1NR4A2NR4A3WDR5ALDH1A1
Bromide SCHEMBL21173947 0.84 NR4A1 (0.62) NR4A1NR4A2NR4A3WDR5ALDH1A1
Fluoride SCHEMBL21331927 0.84 NR4A1 (0.62) NR4A1NR4A2NR4A3WDR5ALDH1A1
SCHEMBL31436579 0.84 NR4A1 (0.62) NR4A1NR4A2NR4A3WDR5ALDH1A1
Hydrochloric Acid SCHEMBL4429797 0.84 NR4A1 (0.62) NR4A1NR4A2NR4A3WDR5ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 340 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 EP claimed
WO-2024167565-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS PURDUE RESEARCH FOUNDATION (US) 2024-08-15 WO claimed
CN-111410603-A Benzanthrone derivative, preparation method thereof and application thereof in functional pigment 上海甘田光学材料有限公司 2020-07-14 CN claimed
US-10072043-B2 Inhibitors of protein tyrosine phosphatases INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2018-09-11 US claimed
US-20160176922-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES Indiana University Research and Technology Corpora tion (US) 2016-06-23 US claimed
US-9217012-B2 Inhibitors of protein tyrosine phosphatases INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2015-12-22 US claimed
US-20120088720-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATI (US) 2012-04-12 US claimed
WO-2010118241-A2 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATION (US) 2010-10-14 WO claimed
US-7732625-B2 Colorant compounds XEROX CORPORATION (US) 2010-06-08 US claimed
US-7311767-B2 Forming a salt of a liquid phase change ink carrier of stearyl stearamide, an amine substituted Xanthene, acridine, anthracene or thioxanthene chromogen, and a metal salt capable of forming a compound with two chromogens XEROX CORPORATION (US) 2007-12-25 US claimed
US-7033424-B2 Phase change inks XEROX CORPORATION (US) 2006-04-25 US claimed
US-20060021546-A1 Processes for preparing phase change inks XEROX CORPORATION 2006-02-02 US claimed
US-20060020141-A1 Metallized dye XEROX CORPORATION 2006-01-26 US claimed
US-20060016369-A1 PHASE CHANGE INKS XEROX CORPORATION 2006-01-26 US claimed
US-6946025-B2 Process for preparing tetra-amide compounds XEROX CORPORATION (US) 2005-09-20 US claimed
US-20050090690-A1 Process for preparing tetra-amide compounds XEROX CORPORATION 2005-04-28 US claimed
EP-0952154-B1 N-acyl and N-aroyl aralkyl amides PFIZER PROD INC (US) 2004-08-18 EP claimed
EP-0952154-A2 N-acyl and N-aroyl aralkyl amides Pfizer Products Inc. (US) 1999-10-27 EP claimed
US-12551555-B2 Compositions and methods for potentiating immune activity KUMQUAT BIOSCIENCES INC. (US) 2026-02-17 US disclosed
US-4224225-A PHOTOPOLYMERIZATION INITIATOR FUJI PHOTO FILM CO., LTD. (JP) 1980-09-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10072043-B2 Inhibitors of protein tyrosine phosphatases PTPRCAP, PTPRF, PTPRS NR4A1 4415/4885NR4A2 3703/4885NR4A3 3566/4885
US-12551555-B2 Compositions and methods for potentiating immune activity PTPRCAP, PTPN2, PTPRC NR4A1 2978/4885NR4A2 1456/4885NR4A3 2587/4885
US-20160176922-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES PTPRCAP, PTPRF, PTPRS NR4A1 4415/4885NR4A2 3703/4885NR4A3 3566/4885
US-20060020141-A1 Metallized dye CDYL, CDY1; CDY1B, CDYL2 NR4A1 381/4885NR4A2 801/4885NR4A3 588/4885
US-20050090690-A1 Process for preparing tetra-amide compounds TAF9, TAF5, TAF1 NR4A1 1369/4885NR4A2 2413/4885NR4A3 2331/4885
US-20120088720-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES PTPRCAP, PTPRF, PTPRS NR4A1 4415/4885NR4A2 3703/4885NR4A3 3566/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.