Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.50 |
| ▸ | HDAC8 known ✓ | Q9BY41 | 1/20 | 0.48 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.62 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.62 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.62 |
| ▸ | LDHA | P00338 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | WDR5 | P61964 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | ATIC | P31939 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3358028 | 1.00 | NR4A1 (0.62) | NR4A1NR4A2NR4A3LDHAALDH1A1 | |
| SCHEMBL28798 | 0.97 | NR4A1 (0.65) | NR4A1NR4A2NR4A3LDHAALDH1A1 | |
| SCHEMBL29406630 | 0.97 | NR4A1 (0.65) | NR4A1NR4A2NR4A3LDHAALDH1A1 | |
| SCHEMBL30838412 | 0.97 | NR4A1 (0.65) | NR4A1NR4A2NR4A3LDHAALDH1A1 | |
| SCHEMBL30838413 | 0.97 | NR4A1 (0.65) | NR4A1NR4A2NR4A3LDHAALDH1A1 | |
| SCHEMBL31436579 | 0.94 | NR4A1 (0.62) | NR4A1NR4A2NR4A3LDHAALDH1A1 | |
| Fluoride SCHEMBL21331927 | 0.94 | NR4A1 (0.62) | NR4A1NR4A2NR4A3LDHAALDH1A1 | |
| Bromide SCHEMBL21173947 | 0.94 | NR4A1 (0.62) | NR4A1NR4A2NR4A3LDHAALDH1A1 | |
| SCHEMBL7738797 | 0.94 | NR4A1 (0.62) | NR4A1NR4A2NR4A3LDHAALDH1A1 | |
| SCHEMBL28397171 | 0.94 | NR4A1 (0.62) | NR4A1NR4A2NR4A3LDHAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 121 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113150381-B | 1, 4-naphthalene dicarboxylic acid di-smoke hydrazide nucleating agent and preparation method thereof | 重庆文理学院 | 2023-08-01 | — | — | CN | claimed |
| US-10730819-B2 | Naphthalenedicarboxylic acid dichloride production method | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2020-08-04 | — | — | US | claimed |
| US-20200115313-A1 | NAPHTHALENEDICARBOXYLIC ACID DICHLORIDE PRODUCTION METHOD | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2020-04-16 | — | — | US | claimed |
| EP-3512905-A1 | METHOD FOR PRODUCING A POLYBENZAZOL POLYMER (P) | BASF SE (DE) | 2019-07-24 | — | — | EP | claimed |
| EP-0040177-B1 | PROCESS FOR THE PREPARATION OF BENZENE OR NAPHTHALENE ALKENYL CARBOXYLIC ACID DERIVATIVES | CIBA-GEIGY AG (CH) | 1983-07-20 | — | — | EP | claimed |
| US-4335054-A | Process for the preparation of alkenylbenzenecarboxylic acid derivatives and alkenylnaphthalenecarboxylic acid derivatives | CIBA-GEIGY CORPORATION (US) | 1982-06-15 | — | — | US | claimed |
| JP-54058785-A | — | — | None | — | — | JP | disclosed |
| WO-2025023065-A1 | POLYCARBONATE-POLYARYLATE RESIN, COATING COMPOSITION, MOLDED BODY, AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR | 出光興産株式会社 | 2025-01-30 | — | — | WO | disclosed |
| CN-112574561-B | Polyimide film and display device comprising same | SK新技术株式会社 | 2024-06-04 | — | — | CN | disclosed |
| US-20240101751-A1 | HOLLOW MICROBALLOON | TOKUYAMA CORPORATION (JP) | 2024-03-28 | — | — | US | disclosed |
| CN-112574458-B | Window covering film and flexible display panel including the same | SK新技术株式会社 | 2024-03-26 | — | — | CN | disclosed |
| CN-112574457-B | Window covering film and flexible display panel including the same | SK新技术株式会社 | 2024-02-23 | — | — | CN | disclosed |
| CN-112574562-B | Polyimide base film and flexible display panel including the same | SK新技术株式会社 | 2024-02-23 | — | — | CN | disclosed |
| US-4335054-A | Process for the preparation of alkenylbenzenecarboxylic acid derivatives and alkenylnaphthalenecarboxylic acid derivatives | CIBA-GEIGY CORPORATION (US) | 1982-06-15 | — | — | US | disclosed |
| US-4172938-A | Process for producing polyamides with lactam or urea solvent and CaCl2 | TEIJIN LIMITED (JP) | 1979-10-30 | — | — | US | disclosed |
| JP-S5458785-A | HEAT-RESISTANT COMPOSITE FILM AND ITS MANUFACTURE | MITSUBISHI RAYON CO LTD | 1979-05-11 | — | — | JP | disclosed |
| US-4058408-A | Bis-benzoxazolyl-naphthalenes as optical brighteners | CIBA-GEIGY CORPORATION (US) | 1977-11-15 | — | — | US | disclosed |
| US-4017483-A | OPTICAL BRIGHTENERS | CIBA-GEIGY CORPORATION (US) | 1977-04-12 | — | — | US | disclosed |
| US-3996202-A | Process for the preparation of sulfonate group containing aromatic polyamides | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-12-07 | — | — | US | disclosed |
| US-3993659-A | Bis-benzoxazolyl-naphthalenes as optical brighteners | CIBA-GEIGY CORPORATION (US) | 1976-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200115313-A1 | NAPHTHALENEDICARBOXYLIC ACID DICHLORIDE PRODUCTION METHOD | DDT, DHODH, DLD | CA2 517/4885HDAC8 3721/4885NR4A1 809/4885 |
| US-10730819-B2 | Naphthalenedicarboxylic acid dichloride production method | DDT, DHODH, DLD | CA2 517/4885HDAC8 3721/4885NR4A1 809/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.