Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | GPR132 | Q9UNW8 | 3/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2495385 | 0.81 | SMN1; SMN2 (0.60) | SMN1; SMN2KMT2AALOX5LMNAHPGD | |
| SCHEMBL2500865 | 0.81 | SMN1; SMN2 (0.60) | SMN1; SMN2KMT2AALOX5LMNAHPGD | |
| SCHEMBL2499312 | 0.81 | HIF1A (0.43) | LMNATSHRFFAR1 | |
| SCHEMBL2495867 | 0.80 | SMN1; SMN2 (0.50) | SMN1; SMN2KMT2AALOX5LMNAHPGD | |
| SCHEMBL2499931 | 0.80 | SMN1; SMN2 (0.50) | SMN1; SMN2KMT2AALOX5LMNAHPGD | |
| SCHEMBL2986567 | 0.75 | ALOX5 (0.67) | SMN1; SMN2KMT2AALOX5LMNAHPGD | |
| SCHEMBL19857059 | 0.75 | KMT2A (0.56) | SMN1; SMN2KMT2AALOX5TSHRMAOB | |
| SCHEMBL19857060 | 0.75 | KMT2A (0.56) | SMN1; SMN2KMT2AALOX5TSHRMAOB | |
| SCHEMBL12500125 | 0.73 | ALOX5 (0.56) | SMN1; SMN2KMT2AALOX5MAOBGPR132 | |
| SCHEMBL16871388 | 0.73 | ALOX5 (0.56) | SMN1; SMN2KMT2AALOX5MAOBGPR132 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8030354-B2 | 2-(5,5-Dimethylcyclopent-1-enyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; metabolic disorders such as type II diabetes | AMGEN INC. (US) | 2011-10-04 | — | — | US | disclosed |