Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.67 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | MAOB | P27338 | 2/20 | 0.58 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.57 |
| ▸ | BCHE | P06276 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | PTGES | O14684 | 1/20 | 0.53 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.51 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.51 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27833465 | 0.91 | ALOX5 (0.67) | ALOX5PTGS1SMN1; SMN2KMT2AMAOB | |
| SCHEMBL14032970 | 0.88 | KMT2A (0.59) | ALOX5PTGS1SMN1; SMN2KMT2AMAOB | |
| SCHEMBL2853880 | 0.87 | ALOX5 (0.63) | ALOX5PTGS1SMN1; SMN2KMT2AMAOB | |
| SCHEMBL9586230 | 0.86 | AKR1C3 (0.70) | ALOX5PTGS1MAOBPTGS2SLC22A6 | |
| SCHEMBL289911 | 0.84 | KMT2A (0.51) | ALOX5PTGS1SMN1; SMN2KMT2AMAOB | |
| SCHEMBL5494784 | 0.84 | KMT2A (0.64) | ALOX5SMN1; SMN2KMT2AMAOBNR4A2 | |
| SCHEMBL28290141 | 0.83 | KMT2A (0.57) | ALOX5SMN1; SMN2KMT2AMAOBNR4A2 | |
| SCHEMBL13802503 | 0.83 | RXRA (0.57) | ALOX5PTGS1MAPTCXCR1CXCR2 | |
| SCHEMBL2885897 | 0.83 | ALOX5 (0.62) | ALOX5PTGS1MAOBNR4A2PTGS2 | |
| SCHEMBL23923495 | 0.83 | KMT2A (0.61) | ALOX5SMN1; SMN2KMT2AMAOBNR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-51133246-A | — | — | None | — | — | JP | disclosed |
| US-7781591-B2 | Substituted 3-cyanopyridines as protein kinase inhibitors | WYETH LLC (US) | 2010-08-24 | — | — | US | disclosed |
| US-20070287708-A1 | Substituted 3-cyanopyridines as protein kinase inhibitors | WYETH LLC | 2007-12-13 | — | — | US | disclosed |
| EP-1244609-B1 | PREPARING METHOD OF 2-PHENYLALKANOIC ACID DERIVATIVES | KOREA RES INST CHEM TECH (KR) | 2003-10-29 | — | — | EP | disclosed |
| EP-1244609-A1 | PREPARING METHOD OF 2-PHENYLALKANOIC ACID DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2002-10-02 | — | — | EP | disclosed |
| WO-2001049648-A1 | PREPARING METHOD OF 2-PHENYLALKANOIC ACID DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2001-07-12 | — | — | WO | disclosed |
| JP-S51133246-A | PROCESS FOR PREPARING 3- BENZYLOXYPHENYLACETIC ACIDS | GRELAN PHARMACEUT CO LTD | 1976-11-18 | — | — | JP | disclosed |
| US-3985779-A | ANTIINFLAMMATORY AND ANALGESIC ACTIVITIES | EISAI CO., LTD. (JA) | 1976-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070287708-A1 | Substituted 3-cyanopyridines as protein kinase inhibitors | CNKSR1, MAP3K1, MAP3K7 | ALOX5 4600/4885PTGS1 704/4885SMN1; SMN2 2880/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.