Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL786399 | 0.84 | CDK2 (0.44) | CCNE1CDK2CDK5FDPS | |
| SCHEMBL23758338 | 0.83 | CDK2 (0.41) | CCNE1CDK2CDK5FDPS | |
| SCHEMBL23475096 | 0.78 | CCNE1 (0.33) | CCNE1CDK2CDK5FDPS | |
| SCHEMBL20780325 | 0.78 | CCNE1 (0.37) | CCNE1CDK2CDK5FDPS | |
| SCHEMBL23734251 | 0.78 | CCNE1 (0.33) | CCNE1CDK2CDK5FDPS | |
| SCHEMBL20753228 | 0.78 | CCNE1 (0.33) | CCNE1CDK2CDK5FDPS | |
| SCHEMBL24941796 | 0.77 | CCNE1 (0.33) | CCNE1CDK2CDK5FDPS | |
| SCHEMBL21610561 | 0.74 | ALDH1A1 (0.31) | CCNE1CDK2CDK5 | |
| SCHEMBL25098845 | 0.74 | CCNE1 (0.31) | CCNE1CDK2CDK5 | |
| SCHEMBL21610741 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086539-A2 | BCAT2 INHIBITORS | AGIOS PHARMACEUTICALS, INC. (US) | 2023-05-19 | — | — | WO | disclosed |
| US-20230021705-A1 | GLP-1R MODULATING COMPOUNDS | GILEAD SCIENCES, INC. | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230021705-A1 | GLP-1R MODULATING COMPOUNDS | GLP1R, GIPR, GPR119 | CCNE1 4870/4885CDK2 3786/4885CDK5 2814/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.