⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL593822 | 0.89 | TERT (0.42) | — | |
| SCHEMBL593619 | 0.89 | TERT (0.42) | — | |
| SCHEMBL27831718 | 0.89 | TERT (0.42) | — | |
| SCHEMBL1899700 | 0.88 | TBXAS1 (0.49) | — | |
| SCHEMBL9216061 | 0.83 | TERT (0.50) | — | |
| SCHEMBL8368761 | 0.80 | TERT (0.44) | — | |
| SCHEMBL285224 | 0.79 | TERT (0.59) | — | |
| SCHEMBL7235494 | 0.79 | — | — | |
| SCHEMBL7358906 | 0.79 | — | — | |
| SCHEMBL27748791 | 0.79 | TERT (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2158199-A1 | PIPERIDINE COMPOUNDS AND USES THEREOF | AstraZeneca AB (SE) | 2010-03-03 | — | — | EP | claimed |
| WO-2008152418-A1 | PIPERIDINE COMPOUNDS AND USES THEREOF | ASTRAZENECA AB (SE) | 2008-12-18 | — | — | WO | claimed |
| WO-2023086383-A1 | SELECT KRAS G12C INHIBITORS AND USES THEREOF | 1200 PHARMA LLC (US) | 2023-05-19 | — | — | WO | disclosed |
| WO-2022266015-A1 | FUSED HETEROARYL COMPOUNDS USEFUL AS ANTICANCER AGENTS | KUMQUAT BIOSCIENCES INC. (US) | 2022-12-22 | — | — | WO | disclosed |
| US-11358957-B2 | Microbiocidal oxadiazole derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2022-06-14 | — | — | US | disclosed |
| US-20200277287-A1 | MICROBIOCIDAL OXADIAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2020-09-03 | — | — | US | disclosed |
| US-20140205537-A1 | LRRK2 INHIBITORS | ZENOBIA THERAPEUTICS, INC. (US) | 2014-07-24 | — | — | US | disclosed |
| WO-2012178015-A2 | LRRK2 INHIBITORS | ZENOBIA THERAPEUTICS, INC. (US) | 2012-12-27 | — | — | WO | disclosed |
| US-8030339-B2 | Imidazole derivatives for the treatment of anxiety and related diseases | NEUROSEARCH A/S (DK) | 2011-10-04 | — | — | US | disclosed |
| CN-1812789-B | Sulfonamide substituted imidazoquinolines | 3M INNOVATION CO LTD | 2010-07-14 | — | — | CN | disclosed |
| EP-2158199-A1 | PIPERIDINE COMPOUNDS AND USES THEREOF | AstraZeneca AB (SE) | 2010-03-03 | — | — | EP | disclosed |
| EP-0455909-A2 | 5-[1-(Imidazol)methyl]-3,3-disubstituted-2(3H) furanone derivatives | MARION MERRELL DOW INC. (US) | 1991-11-13 | — | — | EP | disclosed |
| US-5039691-A | Anticholinergic agents | MARION MERRELL DOW INC. (US) | 1991-08-13 | — | — | US | disclosed |
| US-4307105-A | FUNGICIDES AND BACTERICIDES | E. R. SQUIBB & SONS, INC. (US) | 1981-12-22 | — | — | US | disclosed |
| US-4307105-A | FUNGICIDES AND BACTERICIDES | E. R. SQUIBB & SONS, INC. (US) | 1981-12-22 | — | — | US | disclosed |
| US-4260616-A | FUNGICIDES, BACTERICIDES | E. R. SQUIBB & SONS, INC. (US) | 1981-04-07 | — | — | US | disclosed |
| US-4260616-A | FUNGICIDES, BACTERICIDES | E. R. SQUIBB & SONS, INC. (US) | 1981-04-07 | — | — | US | disclosed |
| US-4248881-A | BACTERICIDES, FUNGICIDES | E. R. SQUIBB & SONS, INC. (US) | 1981-02-03 | — | — | US | disclosed |
| US-4234589-A | FUNGICIDES; BACTERICIDES | E. R. SQUIBB & SONS, INC. (US) | 1980-11-18 | — | — | US | disclosed |
| US-4234589-A | FUNGICIDES; BACTERICIDES | E. R. SQUIBB & SONS, INC. (US) | 1980-11-18 | — | — | US | disclosed |