Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.30 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12460946 | 0.88 | F10 (0.31) | F10 | |
| SCHEMBL12461518 | 0.86 | F10 (0.35) | SIGMAR1F10 | |
| Propylene Oxide SCHEMBL28348097 | 0.69 | ALDH1A1 (0.50) | TSHRALDH1A1SIGMAR1SMN1; SMN2 | |
| SCHEMBL27946380 | 0.63 | TSHR (0.79) | TSHRALDH1A1SIGMAR1LMNA | |
| SCHEMBL2532 | 0.63 | — | — | |
| Propylene Oxide SCHEMBL11245052 | 0.62 | ALDH1A1 (0.59) | TSHRALDH1A1SIGMAR1 | |
| SCHEMBL5323389 | 0.61 | TSHR (0.73) | TSHRALDH1A1SIGMAR1LMNA | |
| SCHEMBL10789228 | 0.61 | TSHR (0.73) | TSHRALDH1A1SIGMAR1LMNA | |
| Methane SCHEMBL9860576 | 0.61 | TSHR (0.73) | TSHRALDH1A1SIGMAR1LMNA | |
| SCHEMBL3692236 | 0.61 | TSHR (0.73) | TSHRALDH1A1SIGMAR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023288253-A1 | SMALL MOLECULES INHIBITORS OF CYCLIC GMP-AMP SYNTHASE (CGAS) | THE SCRIPPS RESEARCH INSTITUTE (US) | 2023-01-19 | — | — | WO | disclosed |