SCHEMBL24960692

SCHEMBL24960692

COC(=O)c1nc(-c2cc(-n3c(=O)cc(C(F)(F)F)n(C)c3=O)c(F)cc2Cl)cs1

nearest known ligand 0.32

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALPL P05186 1/20 0.32
WDR5 P61964 7/20 0.32
PKM P14618 1/20 0.32
TRPA1 O75762 6/20 0.31
TRPV4 Q9HBA0 3/20 0.31
TRPV3 Q8NET8 1/20 0.31
POLB P06746 2/20 0.31
KDM4E B2RXH2 2/20 0.31
HPGD P15428 2/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
MAPT P10636 1/20 0.30
ALDH1A1 P00352 1/20 0.30
GLA P06280 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24961339 0.84 ALPL (0.35) ALPLPKMTRPA1POLBHPGD
SCHEMBL27559360 0.79 GAA (0.36) POLBKDM4EHPGDL3MBTL1MAPT
SCHEMBL30704867 0.79 GAA (0.36) POLBKDM4EHPGDL3MBTL1MAPT
SCHEMBL24960690 0.78 GAA (0.46) PKMPOLBKDM4EHPGDL3MBTL1
SCHEMBL10695874 0.74 BCAT1 (0.34) GAA
SCHEMBL10695876 0.74 BCAT1 (0.34) GAA
SCHEMBL20356698 0.74 KDM4E (0.34) PKMPOLBKDM4EHPGDL3MBTL1
SCHEMBL10573241 0.73 BCAT1 (0.34)
SCHEMBL27692741 0.73 DHODH (0.33) POLBMAPTALDH1A1GAA
SCHEMBL10579666 0.73 BCAT1 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230015308-A1 SUBSTITUTED THIAZOLE AROMATIC RING-BASED COMPOUND AND PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF QINGDAO KINGAGROOT CHEMICAL COMPOUND CO., LTD. (CN) 2023-01-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230015308-A1 SUBSTITUTED THIAZOLE AROMATIC RING-BASED COMPOUND AND PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF WEE1, CBR3, GLRX3 ALPL 1843/4885WDR5 628/4885PKM 2561/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.