SCHEMBL24960965

SCHEMBL24960965

C[C@@H](OC(C)(C)C)[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](CC1CCCCC1)C(=O)N[C@H](CC#N)C[C@@H]1CCNC1=O

nearest known ligand 0.57

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CTSL P07711 6/20 0.57
CTSB P07858 4/20 0.57
CTSS P25774 1/20 0.47
CTSK P43235 1/20 0.47
CAPN1 P07384 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24961121 0.97 CTSL (0.55) CTSLCTSBCTSSCTSKCAPN1
SCHEMBL26224101 0.96 CTSL (0.52) CTSLCTSBCTSSCTSKCAPN1
SCHEMBL26224137 0.93 CTSL (0.51) CTSLCTSBCTSSCTSKCAPN1
SCHEMBL25767601 0.92 CTSL (0.60) CTSLCTSBCTSSCTSKCAPN1
SCHEMBL24691261 0.92 CTSL (0.60) CTSLCTSBCTSSCTSKCAPN1
SCHEMBL24960968 0.92 CTSL (0.56) CTSLCTSBCTSSCTSKCAPN1
SCHEMBL24960967 0.91 CTSL (0.51) CTSLCTSBCTSSCTSKCAPN1
SCHEMBL24960972 0.90 CTSL (0.58) CTSLCTSBCTSSCTSK
SCHEMBL25286227 0.90 CTSL (0.64) CTSLCTSBCTSSCTSKCAPN1
SCHEMBL25286228 0.90 CTSL (0.64) CTSLCTSBCTSSCTSKCAPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230322668-A1 PROTEASE INHIBITORS AS ANTIVIRALS ACEA Therapeutics, Inc. (US) 2023-10-12 US disclosed
US-11753373-B2 Protease inhibitors as antivirals ACEA Therapeutics, Inc. (US) 2023-09-12 US disclosed
US-20230026438-A1 PROTEASE INHIBITORS AS ANTIVIRALS ACEA Therapeutics, Inc. 2023-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230026438-A1 PROTEASE INHIBITORS AS ANTIVIRALS ACE, ACE2, TMPRSS15 CTSL 4/4885CTSB 44/4885CTSS 45/4885
US-11753373-B2 Protease inhibitors as antivirals ACE, ACE2, TMPRSS15 CTSL 4/4885CTSB 44/4885CTSS 45/4885
US-20230322668-A1 PROTEASE INHIBITORS AS ANTIVIRALS ACE, ACE2, TMPRSS15 CTSL 4/4885CTSB 44/4885CTSS 45/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.