SCHEMBL2496175

SCHEMBL2496175

C=CCc1ccc(O[PH](=O)Oc2ccc(CC=C)cc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.59
CYP3A4 P08684 3/20 0.59
SMN1; SMN2 Q16637 2/20 0.59
TP53 P04637 1/20 0.59
ALOX15 P16050 1/20 0.59
TSHR P16473 1/20 0.59
ALOX12 P18054 1/20 0.59
PPARG P37231 2/20 0.40
PPARD Q03181 2/20 0.40
PPARA Q07869 1/20 0.40
XDH P47989 1/20 0.39
MMP2 P08253 1/20 0.39
MAPT P10636 5/20 0.38
GABRA1 P14867 2/20 0.38
GABRB2 P47870 2/20 0.38
KDM4E B2RXH2 1/20 0.38
MEN1 O00255 1/20 0.38
ALDH2 P05091 1/20 0.38
GAA P10253 1/20 0.38
AKR1B1 P15121 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL88416 0.78 ALDH1A1 (0.68) ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15
SCHEMBL9352993 0.78 ALDH1A1 (0.68) ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15
SCHEMBL437832 0.78 ALDH1A1 (0.68) ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15
SCHEMBL173301 0.76 ALDH1A1 (0.64) ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15
SCHEMBL2097190 0.76 ALDH1A1 (0.65) ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15
SCHEMBL2793675 0.76 ALDH1A1 (0.65) ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15
SCHEMBL3744646 0.76 ALDH1A1 (0.65) ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15
SCHEMBL1361766 0.75 ALDH1A1 (0.59) ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15
SCHEMBL3361786 0.74 LTA4H (0.48) TSHRPPARGPPARAMMP2MEN1
Estragole SCHEMBL57204 0.74 ALDH1A1 (1.00) ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8470741-B2 oil-based concentrate which is homogenous for at least 24 hours and which emulsifies readily on dilution into water CRODA AMERICAS LLC (US) 2013-06-25 US claimed
EP-0026132-B1 PROCESS FOR GLOBAL RECOVERY OF URANIUM, RARE EARTH METALS, THORIUM AND YTTRIUM FROM AN ACID SOLUTION RHONE-POULENC CHIMIE DE BASE (FR) 1983-08-24 EP claimed
US-8939125-B2 Method of operating an engine using an ashless consumable lubricant THE LUBRIZOL CORPORATION (US) 2015-01-27 US disclosed
CN-101535388-B Tyre for vehicle wheels comprising a crosslinked elastomeric composition PIRELLI 2012-05-30 CN disclosed
US-20110297122-A1 Method of Operating an Engine Using an Ashless Consumable Lubricant THE LUBRIZOL CORPORATION (US) 2011-12-08 US disclosed
EP-2367918-A1 METHOD OF OPERATING AN ENGINE USING AN ASHLESS CONSUMABLE LUBRICANT The Lubrizol Corporation (US) 2011-09-28 EP disclosed
WO-2010077538-A1 METHOD OF OPERATING AN ENGINE USING AN ASHLESS CONSUMABLE LUBRICANT THE LUBRIZOL CORPORATION (US) 2010-07-08 WO disclosed
US-20090064956-A1 Ashless Consumable Engine Oil THE LUBRIZOL CORPORATION (US) 2009-03-12 US disclosed
EP-1322733-B1 USE OF A LOW-SULFUR CONSUMABLE LUBRICATING OIL TO REDUCE THE LEVEL OF NOx IN AN INTERNAL COMBUSTION ENGINE LUBRIZOL CORP (US) 2009-02-25 EP disclosed
EP-1805285-A2 ASHLESS CONSUMABLE ENGINE OIL THE LUBRIZOL CORPORATION (US) 2007-07-11 EP disclosed
WO-2006047361-A2 ASHLESS CONSUMABLE ENGINE OIL THE LUBRIZOL CORPORATION (US) 2006-05-04 WO disclosed
US-20060089272-A1 Ashless consumable engine oil THE LUBRIZOL CORPORATION (US) 2006-04-27 US disclosed
US-6946037-B2 Silicone remover ECOLAB GMBH & CO. OHG (DE) 2005-09-20 US disclosed
US-6588393-B2 Characterized by the absence of an extreme-pressure additive comprised of metal and phosphorus; poly-alpha-olefin base oil; an acylated polyamine having at least a 10 aliphatic carbon atom substituent (polyisobutylene) as ashless dispersant THE LUBRIZOL CORPORATION 2003-07-08 US disclosed
EP-1322733-A1 A LOW-SULFUR CONSUMABLE LUBRICATING OIL COMPOSITION AND A METHOD OF OPERATING AN INTERNAL COMBUSTION ENGINE USING THE SAME THE LUBRIZOL CORPORATION (US) 2003-07-02 EP disclosed
US-20020053334-A1 Low-sulfur consumable lubricating oil composition and a method of operating an internal combustion engine using the same LUBRIZOL CORPORATION, THE 2002-05-09 US disclosed
US-20020053333-A1 Low-sulfur consumable lubricating oil composition and a method of operating an internal combustion engine using the same LUBRIZOL CORPORATION, THE 2002-05-09 US disclosed
WO-2002024842-A1 A LOW-SULFUR CONSUMABLE LUBRICATING OIL COMPOSITION AND A METHOD OF OPERATING AN INTERNAL COMBUSTION ENGINE USING THE SAME THE LUBRIZOL CORPORATION (US) 2002-03-28 WO disclosed
EP-0026132-A1 Process for global recovery of uranium, rare earth metals, thorium and yttrium from an acid solution RHONE-POULENC CHIMIE DE BASE (FR) 1981-04-01 EP disclosed
US-4172879-A SOLVENT EXTRACTION WITH A DILUTED ORGANIC PHOSPHATE FREEPORT MINERALS COMPANY (US) 1979-10-30 US disclosed