Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KDM1A | O60341 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5330628 | 0.89 | KMT2A (0.49) | EPHX2KMT2AL3MBTL1KDM1AMAOB | |
| SCHEMBL2500839 | 0.76 | RAB9A (0.42) | NPC1RAB9ASMN1; SMN2EPHX2KMT2A | |
| SCHEMBL7098750 | 0.75 | NPC1 (0.44) | NPC1RAB9ASMN1; SMN2EPHX2ALDH1A1 | |
| SCHEMBL14691121 | 0.74 | MAPT (0.38) | CACNA1BNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL26388338 | 0.72 | PPARG (0.42) | CACNA1BNPC1RAB9ASMN1; SMN2EPHX2 | |
| SCHEMBL20769520 | 0.71 | BTK (0.36) | EPHX2KMT2AL3MBTL1KDM1AMAOB | |
| SCHEMBL3077333 | 0.71 | EPHX1 (0.40) | KMT2AL3MBTL1KDM1AMAOB | |
| SCHEMBL24011354 | 0.70 | SMN1; SMN2 (0.70) | NPC1RAB9ASMN1; SMN2EPHX2KMT2A | |
| SCHEMBL20769518 | 0.69 | BTK (0.36) | KMT2AL3MBTL1KDM1AMAOB | |
| SCHEMBL20769504 | 0.69 | BTK (0.36) | KMT2AL3MBTL1KDM1AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8030489-B2 | Ornithine derivative | ASTELLAS PHARMA INC. (JP) | 2011-10-04 | — | — | US | disclosed |