Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2496332 | 0.89 | CACNA1B (0.41) | KMT2AL3MBTL1KDM1AMAOBEPHX2 | |
| SCHEMBL14691121 | 0.77 | MAPT (0.38) | KMT2AL3MBTL1KDM1AMAOBNFKB1 | |
| SCHEMBL5048259 | 0.76 | KMT2A (0.46) | KMT2AL3MBTL1KDM1AMAOBKCNA3 | |
| SCHEMBL25982239 | 0.76 | KMT2A (0.45) | KMT2AL3MBTL1KDM1AMAOBKCNA3 | |
| SCHEMBL25982165 | 0.76 | KMT2A (0.45) | KMT2AL3MBTL1KDM1AMAOBKCNA3 | |
| SCHEMBL960725 | 0.75 | KMT2A (0.45) | KMT2AL3MBTL1KDM1AMAOBKCNA3 | |
| SCHEMBL4980874 | 0.74 | KMT2A (0.52) | KMT2AL3MBTL1KDM1AMAOBKCNA3 | |
| SCHEMBL741638 | 0.74 | KMT2A (0.47) | KMT2AL3MBTL1CTSL | |
| SCHEMBL3077333 | 0.74 | EPHX1 (0.40) | KMT2AL3MBTL1KDM1AMAOBCA1 | |
| SCHEMBL19559839 | 0.74 | ADRB2 (0.52) | KMT2AL3MBTL1CA12CA1CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007092000-A1 | INHIBITORS OF HCV REPLICATION | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-08-16 | — | — | WO | disclosed |
| EP-1776368-A1 | INHIBITORS OF HCV REPLICATION | Bristol-Myers Squibb Company (US) | 2007-04-25 | — | — | EP | disclosed |
| WO-2006020082-A1 | INHIBITORS OF HCV REPLICATION | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-02-23 | — | — | WO | disclosed |