Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 5/20 | 0.55 |
| ▸ | CTSB | P07858 | 4/20 | 0.55 |
| ▸ | CTSS | P25774 | 3/20 | 0.45 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24963581 | 0.89 | CTSL (0.46) | CTSLCTSBCTSSCAPN1 | |
| SCHEMBL24963577 | 0.86 | CTSB (0.70) | CTSLCTSBCTSS | |
| SCHEMBL24965268 | 0.82 | CTSB (0.67) | CTSLCTSBCTSS | |
| SCHEMBL30140702 | 0.77 | CTSL (0.67) | CTSLCTSBCTSS | |
| SCHEMBL24962654 | 0.77 | CTSL (0.67) | CTSLCTSBCTSS | |
| SCHEMBL25855426 | 0.77 | CTSB (0.58) | CTSLCTSBCTSS | |
| SCHEMBL30140688 | 0.76 | CTSL (0.65) | CTSLCTSBCTSS | |
| SCHEMBL24964990 | 0.76 | CTSL (0.65) | CTSLCTSBCTSS | |
| SCHEMBL24962645 | 0.75 | CTSL (0.60) | CTSLCTSBCTSSCAPN1 | |
| SCHEMBL24965204 | 0.75 | CTSL (0.60) | CTSLCTSBCTSSCAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230033285-A1 | Protease Inhibitors for Treatment of Coronavirus Infections | THE SCRIPPS RESEARCH INSTITUTE | 2023-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230033285-A1 | Protease Inhibitors for Treatment of Coronavirus Infections | ACE, ACE2, TMPRSS2 | CTSL 19/4885CTSB 15/4885CTSS 25/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.