Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 4/20 | 0.43 |
| ▸ | CTSB | P07858 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30140613 | 1.00 | CTSL (0.43) | CTSLCTSB | |
| SCHEMBL24964989 | 0.92 | CTSL (0.49) | CTSLCTSB | |
| SCHEMBL24964999 | 0.91 | CTSB (0.52) | CTSLCTSB | |
| SCHEMBL24754585 | 0.90 | CTSL (0.41) | CTSLCTSB | |
| SCHEMBL30140594 | 0.90 | CTSL (0.41) | CTSLCTSB | |
| SCHEMBL24965002 | 0.90 | CTSL (0.41) | CTSLCTSB | |
| SCHEMBL24962650 | 0.87 | CTSL (0.43) | CTSLCTSB | |
| SCHEMBL30140597 | 0.87 | CTSL (0.43) | CTSLCTSB | |
| SCHEMBL24962659 | 0.87 | CTSL (0.43) | CTSLCTSB | |
| SCHEMBL30140608 | 0.87 | CTSL (0.43) | CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230033285-A1 | Protease Inhibitors for Treatment of Coronavirus Infections | THE SCRIPPS RESEARCH INSTITUTE | 2023-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230033285-A1 | Protease Inhibitors for Treatment of Coronavirus Infections | ACE, ACE2, TMPRSS2 | CTSL 19/4885CTSB 15/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.