Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.57 |
| ▸ | CDK1 | P06493 | 1/20 | 0.51 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3253372 | 0.88 | ALOX15 (0.51) | ALOX15CDK1CCNB1KDM4EALDH1A1 | |
| SCHEMBL2452679 | 0.87 | ALOX15 (0.50) | ALOX15CDK1CCNB1KDM4EALDH1A1 | |
| SCHEMBL4396474 | 0.87 | ALOX15 (0.58) | ALOX15CDK1CCNB1KDM4EALDH1A1 | |
| SCHEMBL2452663 | 0.87 | ALOX15 (0.58) | ALOX15CDK1CCNB1KDM4EALDH1A1 | |
| SCHEMBL30457751 | 0.87 | ALOX15 (0.58) | ALOX15CDK1CCNB1KDM4EALDH1A1 | |
| SCHEMBL16486363 | 0.84 | ALOX15 (0.56) | ALOX15CDK1CCNB1KDM4EALDH1A1 | |
| SCHEMBL8349472 | 0.84 | ALOX15 (0.56) | ALOX15CDK1CCNB1KDM4EALDH1A1 | |
| SCHEMBL15564004 | 0.84 | ALOX15 (0.56) | ALOX15CDK1CCNB1KDM4EALDH1A1 | |
| SCHEMBL3253826 | 0.82 | HRH4 (0.50) | ALOX15CDK1CCNB1ALDH1A1KMT2A | |
| SCHEMBL2452832 | 0.81 | ALOX15 (0.45) | ALOX15CDK1CCNB1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2102186-B1 | INDOLES | HOFFMANN LA ROCHE (CH) | 2011-10-05 | — | — | EP | disclosed |