Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | CDK1 | P06493 | 1/20 | 0.55 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.55 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4396474 | 1.00 | ALOX15 (0.58) | ALOX15CDK1CCNB1HRH4KDM4E | |
| SCHEMBL4046142 | 0.88 | RAB9A (0.57) | ALOX15CDK1CCNB1HRH4KDM4E | |
| SCHEMBL2452663 | 0.88 | ALOX15 (0.58) | ALOX15CDK1CCNB1HRH4KDM4E | |
| SCHEMBL2496462 | 0.87 | ALOX15 (0.57) | ALOX15CDK1CCNB1HRH4KDM4E | |
| SCHEMBL3106434 | 0.87 | CDK1 (0.54) | ALOX15CDK1CCNB1HRH4KDM4E | |
| SCHEMBL4373098 | 0.87 | CDK1 (0.54) | ALOX15CDK1CCNB1HRH4KDM4E | |
| SCHEMBL15564004 | 0.86 | ALOX15 (0.56) | ALOX15CDK1CCNB1HRH4KDM4E | |
| SCHEMBL12501328 | 0.86 | CDK1 (0.53) | ALOX15CDK1CCNB1HRH4KDM4E | |
| SCHEMBL8349472 | 0.86 | ALOX15 (0.56) | ALOX15CDK1CCNB1HRH4KDM4E | |
| SCHEMBL16486363 | 0.86 | ALOX15 (0.56) | ALOX15CDK1CCNB1HRH4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111050765-B | Spiro compounds and methods of making and using the same | H.隆德贝克有限公司 | 2024-01-02 | — | — | CN | disclosed |
| CN-110678177-B | Pyrazole MAGL inhibitors | H.隆德贝克有限公司 | 2023-06-13 | — | — | CN | disclosed |