Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KCNJ6 | P48051 | 11/20 | 0.32 |
| ▸ | KCNJ3 | P48549 | 11/20 | 0.32 |
| ▸ | KCNJ5 | P48544 | 10/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | NNMT | P40261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23240277 | 0.81 | DRD2 (0.38) | DRD2DRD4DRD3KDM4EALDH1A1 | |
| SCHEMBL21604007 | 0.78 | DRD2 (0.34) | DRD2DRD4DRD3KDM4EALDH1A1 | |
| SCHEMBL14785716 | 0.75 | POLB (0.41) | DRD2DRD4DRD3KDM4EALDH1A1 | |
| SCHEMBL15935405 | 0.74 | SMN1; SMN2 (0.41) | DRD2DRD4DRD3KDM4EALDH1A1 | |
| SCHEMBL16347382 | 0.74 | KDM4E (0.43) | KDM4EALDH1A1HSD17B10KCNJ6KCNJ3 | |
| SCHEMBL18865799 | 0.74 | USP1 (0.37) | DRD2DRD4DRD3DPP4DPP8 | |
| SCHEMBL23284469 | 0.71 | DRD2 (0.37) | DRD2DRD4DRD3KDM4EALDH1A1 | |
| SCHEMBL973747 | 0.70 | — | — | |
| SCHEMBL22435406 | 0.68 | DRD2 (0.38) | DRD2DRD4DRD3KDM4EALDH1A1 | |
| SCHEMBL21603981 | 0.68 | DRD2 (0.35) | DRD2DRD4DRD3KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023001061-A1 | CDK7 SELECTIVE INHIBITORS AS ANTICANCER AGENTS | JINGRUI BIOPHARMA CO., LTD. (CN) | 2023-01-26 | — | — | WO | disclosed |