Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.44 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10207610 | 1.00 | SMN1; SMN2 (0.50) | SMN1; SMN2PLA2G2APLA2G5ALDH1A1TP53 | |
| SCHEMBL17715216 | 1.00 | SMN1; SMN2 (0.50) | SMN1; SMN2PLA2G2APLA2G5ALDH1A1TP53 | |
| SCHEMBL4622349 | 0.88 | SMN1; SMN2 (0.46) | SMN1; SMN2PLA2G2APLA2G5ALDH1A1TP53 | |
| SCHEMBL11582357 | 0.87 | SMN1; SMN2 (0.56) | SMN1; SMN2PLA2G2APLA2G5TP53GAA | |
| SCHEMBL11582359 | 0.87 | SMN1; SMN2 (0.56) | SMN1; SMN2PLA2G2APLA2G5TP53GAA | |
| SCHEMBL1818420 | 0.85 | SMN1; SMN2 (0.64) | SMN1; SMN2PLA2G2APLA2G5TP53GAA | |
| SCHEMBL5015593 | 0.84 | SMN1; SMN2 (0.41) | SMN1; SMN2PLA2G2APLA2G5ALDH1A1TP53 | |
| SCHEMBL5015591 | 0.84 | SMN1; SMN2 (0.41) | SMN1; SMN2PLA2G2APLA2G5ALDH1A1TP53 | |
| SCHEMBL30317723 | 0.84 | ALDH1A1 (0.55) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL31743456 | 0.84 | SMN1; SMN2 (0.62) | SMN1; SMN2PLA2G2APLA2G5TP53PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230026641-A1 | METHOD FOR PRODUCING PEPTIDE COMPOUND COMPRISING HIGHLY STERICALLY HINDERED AMINO ACID | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230026641-A1 | METHOD FOR PRODUCING PEPTIDE COMPOUND COMPRISING HIGHLY STERICALLY HINDERED AMINO ACID | DNPEP, VIP, NPEPPS | SMN1; SMN2 2268/4885PLA2G2A 4631/4885PLA2G5 4809/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.