SCHEMBL2496563

SCHEMBL2496563

O=C1CC=C(C2=CCCC2)CC1

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TYMP P19971 2/20 0.38
ALDH1A1 P00352 2/20 0.33
CYP3A4 P08684 1/20 0.33
ACMSD Q8TDX5 1/20 0.33
CCNE1 P24864 1/20 0.32
CDK2 P24941 1/20 0.32
MAPT P10636 1/20 0.32
PDE3B Q13370 1/20 0.31
PDE3A Q14432 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5136081 0.80
SCHEMBL15048839 0.77 TYMP (0.40) TYMPALDH1A1CYP3A4ACMSDCCNE1
SCHEMBL604266 0.77 TYMP (0.40) TYMPALDH1A1CYP3A4ACMSDCCNE1
SCHEMBL10406943 0.76 ALDH1A1 (0.42) TYMPALDH1A1CYP3A4ACMSDCCNE1
SCHEMBL3343472 0.72
SCHEMBL28649782 0.72
SCHEMBL1109730 0.72 TYMP (0.41) TYMPALDH1A1CYP3A4ACMSDCCNE1
SCHEMBL5960583 0.69 TYMP (0.39) TYMPALDH1A1CYP3A4ACMSD
SCHEMBL27749433 0.69 TYMP (0.39) TYMPALDH1A1CYP3A4ACMSD
SCHEMBL296554 0.68 TYMP (0.42) TYMPALDH1A1CYP3A4ACMSDCCNE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2011207775-A 4-(CYCLOPENTENYL)CYCLOHEXENONE DERIVATIVE AND METHOD FOR PRODUCING THE SAME SAGAMI CHEMICAL RESEARCH INSTITUTE 2011-10-20 JP disclosed
JP-2011207785-A 4-CYCLOPENTYLCYCLOHEXANONE DERIVATIVE AND METHOD FOR PRODUCING THE SAME SAGAMI CHEMICAL RESEARCH INSTITUTE 2011-10-20 JP disclosed