SCHEMBL24965932

SCHEMBL24965932

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nearest known ligand 0.42

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 6/20 0.42
ARG1 P05089 1/20 0.36
RAB9A P51151 1/20 0.36
DPP7 Q9UHL4 6/20 0.36
DPP8 Q6V1X1 3/20 0.35
LMNA P02545 1/20 0.34
DPP9 Q86TI2 2/20 0.33
PLAU P00749 1/20 0.33
PLAUR Q03405 1/20 0.33
HDAC8 Q9BY41 1/20 0.31
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL435439 0.85 DPP4 (0.49) DPP4ARG1DPP7DPP8DPP9
SCHEMBL30357425 0.81 DPP4 (0.50) DPP4ARG1DPP7DPP8
SCHEMBL20163928 0.80 DPP4 (0.41) DPP4RAB9ADPP7DPP8DPP9
SCHEMBL20163929 0.80 DPP4 (0.41) DPP4RAB9ADPP7DPP8DPP9
SCHEMBL16310466 0.79 DPP4 (0.49) DPP4ARG1DPP7DPP8
SCHEMBL3346333 0.79 DPP4 (0.49) DPP4ARG1DPP7DPP8
SCHEMBL22413877 0.77 DPP7 (0.35) DPP4RAB9ADPP7DPP8LMNA
SCHEMBL4702393 0.76 HSD17B10 (0.46) DPP4KDM4E
SCHEMBL24964924 0.75 RAB9A (0.37) RAB9ALMNA
Trifluoroacetic Acid SCHEMBL20163711 0.74 DPP8 (0.45) DPP4RAB9ADPP7DPP8DPP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230026641-A1 METHOD FOR PRODUCING PEPTIDE COMPOUND COMPRISING HIGHLY STERICALLY HINDERED AMINO ACID CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2023-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230026641-A1 METHOD FOR PRODUCING PEPTIDE COMPOUND COMPRISING HIGHLY STERICALLY HINDERED AMINO ACID DNPEP, VIP, NPEPPS DPP4 123/4885ARG1 303/4885RAB9A 1443/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.