Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 8/20 | 0.50 |
| ▸ | CTSS | P25774 | 8/20 | 0.50 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | PLK1 | P53350 | 2/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19401696 | 1.00 | CTSK (0.50) | CTSKCTSSCAPN1CA2CTSL | |
| SCHEMBL18291443 | 0.89 | CTSS (0.45) | CTSKCTSSCAPN1CA2CTSL | |
| SCHEMBL13567291 | 0.88 | CTSS (0.51) | CTSKCTSSCAPN1CA2CTSL | |
| SCHEMBL24984812 | 0.87 | CTSS (0.44) | CTSKCTSSCAPN1CA2CTSL | |
| SCHEMBL13921014 | 0.86 | CTSK (0.50) | CTSKCTSSCAPN1CA2CTSL | |
| SCHEMBL13921025 | 0.86 | CTSK (0.50) | CTSKCTSSCAPN1CA2CTSL | |
| SCHEMBL23974449 | 0.86 | CTSK (0.51) | CTSKCTSSCAPN1CA2ITGB3 | |
| SCHEMBL21973062 | 0.86 | CAPN1 (0.37) | CTSKCTSSCAPN1CA2PLK1 | |
| SCHEMBL17870152 | 0.85 | CTSK (0.49) | CTSKCTSSCAPN1CA2CTSL | |
| SCHEMBL13934348 | 0.85 | CTSK (0.60) | CTSKCTSSCAPN1CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023001223-A1 | COMPOUNDS AND COMPOSITIONS FOR TARGETED THERAPY OF RENAL DISEASES | SHANGHAI MICURX PHARMACEUTICAL CO., LTD. (CN) | 2023-01-26 | — | — | WO | disclosed |
| WO-2023001224-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR TARGETED THERAPY OF RENAL CANCERS | SHANGHAI MICURX PHARMACEUTICAL CO., LTD. (CN) | 2023-01-26 | — | — | WO | disclosed |