Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 5/20 | 0.41 |
| ▸ | RARA | P10276 | 4/20 | 0.41 |
| ▸ | RARG | P13631 | 2/20 | 0.41 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.40 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.40 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.40 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 6/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 6/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | CTSV | O60911 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | PTGFR | P43088 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17658331 | 0.88 | KDM4E (0.40) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL10020940 | 0.88 | MAOB (0.39) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL29563554 | 0.88 | KDM4E (0.40) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL190082 | 0.87 | DGAT1 (0.44) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL2407352 | 0.86 | EPHX2 (0.44) | EPHX2NR1H4RARBRARARARG | |
| SCHEMBL2411518 | 0.86 | GAA (0.44) | EPHX2NR1H4ABCC9ABCC8KCNJ11 | |
| SCHEMBL29644326 | 0.86 | GAA (0.44) | EPHX2NR1H4ABCC9ABCC8KCNJ11 | |
| SCHEMBL582706 | 0.85 | POLB (0.44) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL12321278 | 0.83 | NPC1 (0.39) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL753288 | 0.83 | EPHX2 (0.46) | EPHX2NR1H4RARBRARARARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3527556-B1 | METHOD FOR PREPARING DEUTERATED IMIDAZOLE DIKETONE COMPOUND | HINOVA PHARMACEUTICALS INC (CN) | 2023-01-25 | — | — | EP | disclosed |