Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 4/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CLK1 | P49759 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | KDM5A | P29375 | 1/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23234260 | 1.00 | ALDH1A1 (0.42) | ALDH1A1TDP1BRD4ATMFAAH | |
| SCHEMBL24966194 | 0.90 | BRD4 (0.40) | ALDH1A1TDP1BRD4ATMFAAH | |
| SCHEMBL24966219 | 0.86 | BRD4 (0.40) | ALDH1A1TDP1BRD4ATMFAAH | |
| SCHEMBL24966734 | 0.86 | PDCD1 (0.40) | ALDH1A1TDP1BRD4ATMFAAH | |
| SCHEMBL24967057 | 0.86 | BRD4 (0.38) | ALDH1A1TDP1BRD4ATMFAAH | |
| SCHEMBL24966999 | 0.85 | BRD4 (0.37) | ALDH1A1TDP1BRD4ATMFAAH | |
| SCHEMBL24966776 | 0.84 | CYP1A2 (0.51) | ALDH1A1KDM4ELMNAHSD17B10HPGD | |
| SCHEMBL24966742 | 0.84 | BRD4 (0.36) | ALDH1A1TDP1BRD4ATMFAAH | |
| SCHEMBL24966901 | 0.82 | ALDH1A1 (0.42) | ALDH1A1TDP1BRD4ATMFAAH | |
| SCHEMBL24966146 | 0.82 | ALDH1A1 (0.42) | ALDH1A1TDP1BRD4ATMFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230026724-A1 | SUBSTITUTED NITROGEN HETEROCYCLIC COMPOUND AND ANESTHETIC EFFECT THEREOF | CHENGDU MFS PHARMA. CO., LTD. (CN) | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230026724-A1 | SUBSTITUTED NITROGEN HETEROCYCLIC COMPOUND AND ANESTHETIC EFFECT THEREOF | CYP21A2, CYP11B1, CYP11B2 | ALDH1A1 413/4885TDP1 3560/4885BRD4 2260/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.