Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.30 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.30 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24966840 | 0.88 | BRD4 (0.32) | ALDH1A1BRD4MAPK1FAAHCYP1A2 | |
| SCHEMBL24967068 | 0.88 | BRD4 (0.31) | BRD4MAPK1FAAHCYP1A2CYP3A4 | |
| SCHEMBL24966869 | 0.82 | PDCD1 (0.39) | ALDH1A1BRD4MAPK1FAAHCYP1A2 | |
| SCHEMBL22696807 | 0.81 | MEN1 (0.34) | ALDH1A1BRD4MAPK1CYP1A2CYP3A4 | |
| SCHEMBL22696920 | 0.81 | MAPK1 (0.38) | ALDH1A1MAPK1CYP1A2CYP3A4GABRA1 | |
| SCHEMBL24966873 | 0.80 | CYP1A2 (0.35) | ALDH1A1BRD4MAPK1FAAHCYP1A2 | |
| SCHEMBL23234254 | 0.79 | BRD4 (0.37) | ALDH1A1BRD4MAPK1FAAHCYP1A2 | |
| SCHEMBL24966821 | 0.78 | CYP3A4 (0.42) | ALDH1A1MAPK1CYP1A2CYP3A4GABRA1 | |
| SCHEMBL24966083 | 0.78 | BRD4 (0.35) | ALDH1A1BRD4MAPK1FAAHCYP1A2 | |
| SCHEMBL24966901 | 0.75 | ALDH1A1 (0.42) | ALDH1A1BRD4MAPK1FAAHLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230026724-A1 | SUBSTITUTED NITROGEN HETEROCYCLIC COMPOUND AND ANESTHETIC EFFECT THEREOF | CHENGDU MFS PHARMA. CO., LTD. (CN) | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230026724-A1 | SUBSTITUTED NITROGEN HETEROCYCLIC COMPOUND AND ANESTHETIC EFFECT THEREOF | CYP21A2, CYP11B1, CYP11B2 | ALDH1A1 413/4885BRD4 2260/4885MAPK1 1577/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.