Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | PRKDC | P78527 | 5/20 | 0.36 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 2/20 | 0.34 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | PLK4 | O00444 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | PRKCG | P05129 | 1/20 | 0.31 |
| ▸ | INSR | P06213 | 1/20 | 0.31 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
| ▸ | KIT | P10721 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.31 |
| ▸ | MARK3 | P27448 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21936571 | 0.92 | ALDH1A1 (0.33) | ALOX5PRKDCCDK2PIK3CDPIK3CB | |
| SCHEMBL19524878 | 0.85 | KDM4E (0.33) | ALOX5PRKDCPTGES2PIK3CDPIK3CB | |
| SCHEMBL25000266 | 0.84 | ALDH1A1 (0.42) | ATMKDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL23584424 | 0.84 | ALOX5 (0.41) | ALOX5PRKDCPTGES2GGPS1PRMT5 | |
| SCHEMBL24627623 | 0.84 | ALOX5 (0.41) | ALOX5PRKDCPTGES2GGPS1PRMT5 | |
| SCHEMBL24118933 | 0.84 | ALOX5 (0.41) | ALOX5PRKDCPTGES2GGPS1PRMT5 | |
| SCHEMBL16067898 | 0.84 | ALOX5 (0.41) | ALOX5PRKDCPTGES2GGPS1PRMT5 | |
| SCHEMBL21784249 | 0.83 | PRKDC (0.39) | ALOX5PRKDCPTGES2GGPS1PRMT5 | |
| SCHEMBL75000 | 0.83 | ALOX5 (0.59) | ALOX5PRKDCPTGES2CDK2GGPS1 | |
| SCHEMBL31593186 | 0.83 | ALOX5 (0.59) | ALOX5PRKDCPTGES2CDK2GGPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3856868-B1 | COMPOUNDS THAT CAN BE USED IN AN ORGANIC ELECTRONIC DEVICE AS ACTIVE COMPOUNDS | MERCK PATENT GMBH (DE) | 2023-01-25 | — | — | EP | disclosed |