Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 1/20 | 0.55 |
| ▸ | ERN1 | O75460 | 1/20 | 0.55 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.55 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.55 |
| ▸ | SRC | P12931 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24804343 | 0.86 | CA12 (0.46) | TLR2ERN1TLR1TLR6CA1 | |
| SCHEMBL807200 | 0.84 | TLR2 (0.62) | TLR2ERN1TLR1TLR6SRC | |
| SCHEMBL4645064 | 0.83 | SRC (0.59) | TLR2ERN1TLR1TLR6SRC | |
| SCHEMBL16112334 | 0.83 | SRC (0.62) | TLR2ERN1TLR1TLR6SRC | |
| SCHEMBL31223205 | 0.82 | ALDH1A1 (0.50) | TLR2ERN1TLR1TLR6SRC | |
| SCHEMBL8413248 | 0.82 | ALDH1A1 (0.50) | TLR2ERN1TLR1TLR6SRC | |
| SCHEMBL16048364 | 0.81 | SRC (0.60) | TLR2ERN1TLR1TLR6SRC | |
| SCHEMBL24810562 | 0.81 | SRC (0.56) | TLR2ERN1TLR1TLR6SRC | |
| SCHEMBL1665129 | 0.80 | SRC (0.59) | TLR2ERN1TLR1TLR6SRC | |
| SCHEMBL15495905 | 0.80 | MAPT (0.47) | TLR2ERN1TLR1TLR6CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024092041-A1 | CURABLE COMPOSITIONS COMPRISING A POLYMERIZABLE REACTIVE DILUENT FOR FABRICATION OF ORTHODONTIC APPLIANCES | ALIGN TECHNOLOGY, INC. (US) | 2024-05-02 | — | — | WO | disclosed |
| WO-2023130034-A1 | DEVICES AND METHODS FOR CONTROLLING PARTICLE DISTRIBUTION IN POLYMERS | ALIGN TECHNOLOGY, INC. (US) | 2023-07-06 | — | — | WO | disclosed |
| US-20230021953-A1 | MULTI-VALENT POLYMERIZABLE COMPOSITIONS AND METHODS OF PRODUCING AND USING THE SAME | ALIGN TECHNOLOGY, INC. | 2023-01-26 | — | — | US | disclosed |