Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP5 | Q01469 | 3/20 | 0.51 |
| ▸ | FABP7 | O15540 | 2/20 | 0.51 |
| ▸ | TLR2 | O60603 | 4/20 | 0.42 |
| ▸ | TLR1 | Q15399 | 4/20 | 0.42 |
| ▸ | PPARG | P37231 | 4/20 | 0.42 |
| ▸ | PPARA | Q07869 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | F10 | P00742 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 2/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24967216 | 0.92 | FABP5 (0.44) | FABP5FABP7TLR2TLR1PPARG | |
| SCHEMBL24967215 | 0.92 | FABP5 (0.44) | FABP5FABP7TLR2TLR1PPARG | |
| SCHEMBL24967724 | 0.92 | FABP5 (0.44) | FABP5FABP7TLR2TLR1PPARG | |
| SCHEMBL24967716 | 0.92 | FABP5 (0.44) | FABP5FABP7TLR2TLR1PPARG | |
| SCHEMBL24967825 | 0.90 | FABP5 (0.43) | FABP5FABP7PPARGPPARAKMT2A | |
| SCHEMBL24967722 | 0.89 | PPARG (0.47) | FABP5FABP7TLR2TLR1PPARG | |
| SCHEMBL24967723 | 0.89 | FABP5 (0.44) | FABP5FABP7TLR2TLR1PPARG | |
| SCHEMBL6375144 | 0.83 | FABP5 (0.53) | FABP5FABP7KMT2AF10EPHX2 | |
| SCHEMBL119453 | 0.83 | FABP5 (0.52) | FABP5FABP7KMT2AF10EPHX2 | |
| SCHEMBL4709998 | 0.80 | FABP5 (0.49) | FABP5FABP7KMT2AF10EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192340-A9 | SMALL MOLECULE ALLOSTERIC MODULATORS OF CLASS B GPCR, THE PTHR, AND METHOD TO IDENTIFY THEM | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2023-02-02 | — | — | WO | disclosed |