Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP5 | Q01469 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 3/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | FABP7 | O15540 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.42 |
| ▸ | EDNRA | P25101 | 2/20 | 0.42 |
| ▸ | EDNRB | P24530 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24967824 | 0.90 | FABP5 (0.51) | FABP5PPARGPPARAFABP7PDE4B | |
| SCHEMBL24967716 | 0.89 | FABP5 (0.44) | FABP5PPARGPPARAFABP7PDE4B | |
| SCHEMBL24967216 | 0.87 | FABP5 (0.44) | FABP5PPARGPPARAFABP7MDM2 | |
| SCHEMBL24967215 | 0.87 | FABP5 (0.44) | FABP5PPARGPPARAFABP7MDM2 | |
| SCHEMBL24967724 | 0.87 | FABP5 (0.44) | FABP5PPARGPPARAFABP7PDE4B | |
| SCHEMBL24967722 | 0.82 | PPARG (0.47) | FABP5PPARGPPARAFABP7PDE4B | |
| SCHEMBL24967723 | 0.80 | FABP5 (0.44) | FABP5PPARGPPARAFABP7PDE4B | |
| SCHEMBL24967230 | 0.79 | EDNRA (0.38) | FABP5PPARGPPARAFABP7EDNRA | |
| SCHEMBL23924125 | 0.77 | ALDH1A1 (0.48) | PDE4BEDNRAEDNRBALDH1A1MEN1 | |
| SCHEMBL20475203 | 0.77 | ALDH1A1 (0.48) | PDE4BEDNRAEDNRBALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192340-A9 | SMALL MOLECULE ALLOSTERIC MODULATORS OF CLASS B GPCR, THE PTHR, AND METHOD TO IDENTIFY THEM | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2023-02-02 | — | — | WO | disclosed |