Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 8/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.47 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.43 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24968483 | 0.87 | FGFR4 (0.41) | NR4A2MAPTHTTL3MBTL1MAOB | |
| SCHEMBL24968481 | 0.80 | EGFR (0.47) | NR4A2L3MBTL1MAOBFFAR4MRGPRX4 | |
| SCHEMBL30152313 | 0.80 | EGFR (0.47) | NR4A2L3MBTL1MAOBFFAR4MRGPRX4 | |
| SCHEMBL29824938 | 0.78 | L3MBTL1 (0.50) | NR4A2MAPTHTTL3MBTL1MAOB | |
| SCHEMBL23591751 | 0.78 | L3MBTL1 (0.50) | NR4A2MAPTHTTL3MBTL1MAOB | |
| SCHEMBL3042071 | 0.74 | MAOB (0.58) | NR4A2MAPTHTTL3MBTL1MAOB | |
| SCHEMBL24968496 | 0.73 | MAOB (0.57) | NR4A2MAOBMRGPRX4 | |
| SCHEMBL29824502 | 0.72 | MRGPRX4 (0.59) | NR4A2L3MBTL1MAOBFFAR4MRGPRX4 | |
| SCHEMBL23591727 | 0.72 | MRGPRX4 (0.59) | NR4A2L3MBTL1MAOBFFAR4MRGPRX4 | |
| SCHEMBL24969151 | 0.71 | S1PR1 (0.52) | NR4A2L3MBTL1MAOBFFAR4MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009785-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2023-02-02 | — | — | WO | disclosed |