Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.47 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.44 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | TEK | Q02763 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30152313 | 1.00 | EGFR (0.47) | EGFRLRRK2MAOBALDH1A1GAA | |
| SCHEMBL30152371 | 0.87 | EGFR (0.56) | EGFRMRGPRX4ERBB2ERBB4 | |
| SCHEMBL24968448 | 0.87 | EGFR (0.56) | EGFRMRGPRX4ERBB2ERBB4 | |
| SCHEMBL24968478 | 0.87 | TGM2 (0.43) | EGFRLRRK2TGM2 | |
| SCHEMBL24969151 | 0.86 | S1PR1 (0.52) | EGFRLRRK2MAOBALDH1A1GAA | |
| SCHEMBL24968472 | 0.82 | EGFR (0.45) | EGFRALDH1A1MRGPRX4ERBB2ERBB4 | |
| SCHEMBL24968495 | 0.80 | NR4A2 (0.52) | MAOBL3MBTL1MRGPRX4NR4A2FFAR4 | |
| SCHEMBL23591751 | 0.78 | L3MBTL1 (0.50) | MAOBALDH1A1GAAL3MBTL1MRGPRX4 | |
| SCHEMBL29824938 | 0.78 | L3MBTL1 (0.50) | MAOBALDH1A1GAAL3MBTL1MRGPRX4 | |
| SCHEMBL24969149 | 0.77 | EGFR (0.48) | EGFRLRRK2MRGPRX4ERBB2ERBB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009785-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2023-02-02 | — | — | WO | disclosed |